FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970252802> ?p ?o ?g. }

• W1970252802 endingPage "3429" @default.
• W1970252802 startingPage "3424" @default.
• W1970252802 abstract "VCP/p97 is a multifunctional AAA+-ATPase involved in vesicle fusion, proteasomal degradation, and autophagy. Reported dysfunctions of these processes in Alzheimer disease (AD), along with the linkage of VCP/p97 to inclusion body myopathy with Paget's disease and frontotemporal dementia (IBMPFD) led us to examine the possible linkage of VCP to the AD-relevant protein, tau. VCP levels were reduced in AD brains, but not in the cerebral cortex of an AD mouse model, suggesting that VCP reduction occurs upstream of tau pathology. Genetic reduction of VCP in a primary neuronal model led to increases in the levels of tau phosphorylated at Ser(262/356), indicating that VCP may be involved in regulating post-translational processing of tau in AD, demonstrating a possible functional linkage between tau and VCP." @default.
• W1970252802 created "2016-06-24" @default.
• W1970252802 creator A5022050972 @default.
• W1970252802 creator A5025207687 @default.
• W1970252802 creator A5039518106 @default.
• W1970252802 creator A5062150026 @default.
• W1970252802 date "2011-10-04" @default.
• W1970252802 modified "2023-10-16" @default.
• W1970252802 title "Decreases in valosin-containing protein result in increased levels of tau phosphorylated at Ser262/356" @default.
• W1970252802 cites W1671523129 @default.
• W1970252802 cites W1919353 @default.
• W1970252802 cites W1966993307 @default.
• W1970252802 cites W1967464880 @default.
• W1970252802 cites W1978922366 @default.
• W1970252802 cites W1989171146 @default.
• W1970252802 cites W1989634299 @default.
• W1970252802 cites W2002659179 @default.
• W1970252802 cites W2003772355 @default.
• W1970252802 cites W2013037750 @default.
• W1970252802 cites W2013581014 @default.
• W1970252802 cites W2017433575 @default.
• W1970252802 cites W2043637943 @default.
• W1970252802 cites W2043712143 @default.
• W1970252802 cites W2044025216 @default.
• W1970252802 cites W2047455709 @default.
• W1970252802 cites W2055064377 @default.
• W1970252802 cites W2056607803 @default.
• W1970252802 cites W2059584015 @default.
• W1970252802 cites W2064797576 @default.
• W1970252802 cites W2066107334 @default.
• W1970252802 cites W2076032638 @default.
• W1970252802 cites W2079196169 @default.
• W1970252802 cites W2085939493 @default.
• W1970252802 cites W2086457894 @default.
• W1970252802 cites W2091829752 @default.
• W1970252802 cites W2120947942 @default.
• W1970252802 cites W2141284487 @default.
• W1970252802 cites W2146969978 @default.
• W1970252802 doi "https://doi.org/10.1016/j.febslet.2011.09.032" @default.
• W1970252802 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3209510" @default.
• W1970252802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21983102" @default.
• W1970252802 hasPublicationYear "2011" @default.
• W1970252802 type Work @default.
• W1970252802 sameAs 1970252802 @default.
• W1970252802 citedByCount "8" @default.
• W1970252802 countsByYear W19702528022013 @default.
• W1970252802 countsByYear W19702528022014 @default.
• W1970252802 countsByYear W19702528022015 @default.
• W1970252802 countsByYear W19702528022016 @default.
• W1970252802 countsByYear W19702528022022 @default.
• W1970252802 countsByYear W19702528022023 @default.
• W1970252802 crossrefType "journal-article" @default.
• W1970252802 hasAuthorship W1970252802A5022050972 @default.
• W1970252802 hasAuthorship W1970252802A5025207687 @default.
• W1970252802 hasAuthorship W1970252802A5039518106 @default.
• W1970252802 hasAuthorship W1970252802A5062150026 @default.
• W1970252802 hasBestOaLocation W19702528021 @default.
• W1970252802 hasConcept C101635128 @default.
• W1970252802 hasConcept C11960822 @default.
• W1970252802 hasConcept C126322002 @default.
• W1970252802 hasConcept C169760540 @default.
• W1970252802 hasConcept C181199279 @default.
• W1970252802 hasConcept C185592680 @default.
• W1970252802 hasConcept C190283241 @default.
• W1970252802 hasConcept C203522944 @default.
• W1970252802 hasConcept C23265538 @default.
• W1970252802 hasConcept C2777898937 @default.
• W1970252802 hasConcept C2778641062 @default.
• W1970252802 hasConcept C2778670691 @default.
• W1970252802 hasConcept C2779134260 @default.
• W1970252802 hasConcept C2779483572 @default.
• W1970252802 hasConcept C502032728 @default.
• W1970252802 hasConcept C55493867 @default.
• W1970252802 hasConcept C71924100 @default.
• W1970252802 hasConcept C86803240 @default.
• W1970252802 hasConcept C95444343 @default.
• W1970252802 hasConceptScore W1970252802C101635128 @default.
• W1970252802 hasConceptScore W1970252802C11960822 @default.
• W1970252802 hasConceptScore W1970252802C126322002 @default.
• W1970252802 hasConceptScore W1970252802C169760540 @default.
• W1970252802 hasConceptScore W1970252802C181199279 @default.
• W1970252802 hasConceptScore W1970252802C185592680 @default.
• W1970252802 hasConceptScore W1970252802C190283241 @default.
• W1970252802 hasConceptScore W1970252802C203522944 @default.
• W1970252802 hasConceptScore W1970252802C23265538 @default.
• W1970252802 hasConceptScore W1970252802C2777898937 @default.
• W1970252802 hasConceptScore W1970252802C2778641062 @default.
• W1970252802 hasConceptScore W1970252802C2778670691 @default.
• W1970252802 hasConceptScore W1970252802C2779134260 @default.
• W1970252802 hasConceptScore W1970252802C2779483572 @default.
• W1970252802 hasConceptScore W1970252802C502032728 @default.
• W1970252802 hasConceptScore W1970252802C55493867 @default.
• W1970252802 hasConceptScore W1970252802C71924100 @default.
• W1970252802 hasConceptScore W1970252802C86803240 @default.
• W1970252802 hasConceptScore W1970252802C95444343 @default.
• W1970252802 hasIssue "21" @default.
• W1970252802 hasLocation W19702528021 @default.
• W1970252802 hasLocation W19702528022 @default.

• next