FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970258105> ?p ?o ?g. }

• W1970258105 endingPage "437" @default.
• W1970258105 startingPage "433" @default.
• W1970258105 abstract "The D allele of the angiotensin-converting enzyme (ACE) gene has been linked with diabetic nephropathy and IgA glomerulonephritis and with faster renal disease progression. The association of this allele with nephroangiosclerosis has been scarcely investigated. We have tested this association in 45 hypertensive patients (all whites) with well defined nephroangiosclerosis (diagnosis established on the basis of renal biopsy in all cases) and moderate to severe renal failure. As studies of genetic association of small size often produce conflicting results, besides a control group of 343 Italian patients with essential hypertension and normal renal function, we elected to use also a very large control group of race-matched subjects taken from a meta-analysis of 27,565 whites. The proportion of patients with the D allele (64%) was higher in patients with nephroangiosclerosis than that in Italian hypertensives (54%) and in whites (54%). DD and DI genotypes were more prevalent in patients than in control groups. The dominant model (DD and DI v II: nephroangiosclerosis v Italian controls: chi2 = 6.19, P = .012; nephroangiosclerosis v whites chi2 = 6.86, P = .009) fitted the data better than the codominant and the recessive model (P < or = .022). The D allele is associated with nephroangiosclerosis with a dominant effect in the sample of patients studied. Although intervention studies are needed to see whether these findings imply a causal association, our data suggest that this allele may at least act as disease marker in nephroangiosclerosis." @default.
• W1970258105 created "2016-06-24" @default.
• W1970258105 creator A5004299194 @default.
• W1970258105 creator A5004659098 @default.
• W1970258105 creator A5012409706 @default.
• W1970258105 creator A5027465947 @default.
• W1970258105 creator A5054081924 @default.
• W1970258105 creator A5065714184 @default.
• W1970258105 creator A5073724502 @default.
• W1970258105 creator A5075694246 @default.
• W1970258105 creator A5079088163 @default.
• W1970258105 creator A5091031321 @default.
• W1970258105 date "2000-04-01" @default.
• W1970258105 modified "2023-10-15" @default.
• W1970258105 title "The deletion polymorphism of the angiotensin-converting enzyme is associated with nephroangiosclerosis" @default.
• W1970258105 cites W1994834210 @default.
• W1970258105 cites W1999767397 @default.
• W1970258105 cites W2013709047 @default.
• W1970258105 cites W2014811858 @default.
• W1970258105 cites W2022028563 @default.
• W1970258105 cites W2034331149 @default.
• W1970258105 cites W2036018698 @default.
• W1970258105 cites W2053300426 @default.
• W1970258105 cites W2057672660 @default.
• W1970258105 cites W2069126646 @default.
• W1970258105 cites W2074323470 @default.
• W1970258105 cites W2077776851 @default.
• W1970258105 cites W2111202889 @default.
• W1970258105 cites W2114036978 @default.
• W1970258105 cites W2331379601 @default.
• W1970258105 cites W2404174567 @default.
• W1970258105 cites W2409939433 @default.
• W1970258105 doi "https://doi.org/10.1016/s0895-7061(99)00195-8" @default.
• W1970258105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10821348" @default.
• W1970258105 hasPublicationYear "2000" @default.
• W1970258105 type Work @default.
• W1970258105 sameAs 1970258105 @default.
• W1970258105 citedByCount "21" @default.
• W1970258105 countsByYear W19702581052013 @default.
• W1970258105 countsByYear W19702581052015 @default.
• W1970258105 countsByYear W19702581052016 @default.
• W1970258105 countsByYear W19702581052018 @default.
• W1970258105 countsByYear W19702581052023 @default.
• W1970258105 crossrefType "journal-article" @default.
• W1970258105 hasAuthorship W1970258105A5004299194 @default.
• W1970258105 hasAuthorship W1970258105A5004659098 @default.
• W1970258105 hasAuthorship W1970258105A5012409706 @default.
• W1970258105 hasAuthorship W1970258105A5027465947 @default.
• W1970258105 hasAuthorship W1970258105A5054081924 @default.
• W1970258105 hasAuthorship W1970258105A5065714184 @default.
• W1970258105 hasAuthorship W1970258105A5073724502 @default.
• W1970258105 hasAuthorship W1970258105A5075694246 @default.
• W1970258105 hasAuthorship W1970258105A5079088163 @default.
• W1970258105 hasAuthorship W1970258105A5091031321 @default.
• W1970258105 hasBestOaLocation W19702581051 @default.
• W1970258105 hasConcept C104317684 @default.
• W1970258105 hasConcept C126322002 @default.
• W1970258105 hasConcept C134018914 @default.
• W1970258105 hasConcept C135763542 @default.
• W1970258105 hasConcept C159641895 @default.
• W1970258105 hasConcept C180754005 @default.
• W1970258105 hasConcept C27016395 @default.
• W1970258105 hasConcept C2778653478 @default.
• W1970258105 hasConcept C2779922275 @default.
• W1970258105 hasConcept C2780091579 @default.
• W1970258105 hasConcept C2781184683 @default.
• W1970258105 hasConcept C37463918 @default.
• W1970258105 hasConcept C54355233 @default.
• W1970258105 hasConcept C555293320 @default.
• W1970258105 hasConcept C71924100 @default.
• W1970258105 hasConcept C84393581 @default.
• W1970258105 hasConcept C86803240 @default.
• W1970258105 hasConcept C90924648 @default.
• W1970258105 hasConceptScore W1970258105C104317684 @default.
• W1970258105 hasConceptScore W1970258105C126322002 @default.
• W1970258105 hasConceptScore W1970258105C134018914 @default.
• W1970258105 hasConceptScore W1970258105C135763542 @default.
• W1970258105 hasConceptScore W1970258105C159641895 @default.
• W1970258105 hasConceptScore W1970258105C180754005 @default.
• W1970258105 hasConceptScore W1970258105C27016395 @default.
• W1970258105 hasConceptScore W1970258105C2778653478 @default.
• W1970258105 hasConceptScore W1970258105C2779922275 @default.
• W1970258105 hasConceptScore W1970258105C2780091579 @default.
• W1970258105 hasConceptScore W1970258105C2781184683 @default.
• W1970258105 hasConceptScore W1970258105C37463918 @default.
• W1970258105 hasConceptScore W1970258105C54355233 @default.
• W1970258105 hasConceptScore W1970258105C555293320 @default.
• W1970258105 hasConceptScore W1970258105C71924100 @default.
• W1970258105 hasConceptScore W1970258105C84393581 @default.
• W1970258105 hasConceptScore W1970258105C86803240 @default.
• W1970258105 hasConceptScore W1970258105C90924648 @default.
• W1970258105 hasIssue "4" @default.
• W1970258105 hasLocation W19702581051 @default.
• W1970258105 hasLocation W19702581052 @default.
• W1970258105 hasOpenAccess W1970258105 @default.
• W1970258105 hasPrimaryLocation W19702581051 @default.
• W1970258105 hasRelatedWork W165951312 @default.
• W1970258105 hasRelatedWork W1982283545 @default.

• next