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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970278999> ?p ?o ?g. }

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• W1970278999 abstract "Electric field driven transport of DNA through solid-state nanopores is the key process in nanopore-based DNA sequencing that promises dramatic reduction of genome sequencing costs. A major hurdle in the development of this sequencing method is that DNA transport through the nanopores occurs too quickly for the DNA sequence to be detected. By means of all-atom molecular dynamics simulations, we demonstrate that the velocity of DNA transport through a nanopore can be controlled by the charge state of the nanopore surface. In particular, we show that the charge density of the nanopore surface controls the magnitude and/or direction of the electro-osmotic flow through the nanopore and thereby can significantly reduce or even reverse the effective electrophoretic force on DNA. Our work suggests a physical mechanism to control DNA transport in a nanopore by chemical, electrical or electrochemical modification of the nanopore surface." @default.
• W1970278999 created "2016-06-24" @default.
• W1970278999 creator A5024825409 @default.
• W1970278999 creator A5076175038 @default.
• W1970278999 date "2010-10-29" @default.
• W1970278999 modified "2023-09-25" @default.
• W1970278999 title "Control and reversal of the electrophoretic force on DNA in a charged nanopore" @default.
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• W1970278999 doi "https://doi.org/10.1088/0953-8984/22/45/454123" @default.
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