FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970314102> ?p ?o ?g. }

• W1970314102 endingPage "22" @default.
• W1970314102 startingPage "9" @default.
• W1970314102 abstract "There is increasing motivation to develop clinically relevant experimental models for cervical SCI in rodents and techniques to assess deficits in forelimb function. Here we describe a bilateral cervical contusion model in rats. Female Sprague-Dawley rats received mild or moderate cervical contusion injuries (using the Infinite Horizons device) at C5, C6, or C7/8. Forelimb motor function was assessed using a grip strength meter (GSM); sensory function was assessed by the von Frey hair test; the integrity of the corticospinal tract (CST) was assessed by biotinylated dextran amine (BDA) tract tracing. Mild contusions caused primarily dorsal column (DC) and gray matter (GM) damage while moderate contusions produced additional damage to lateral and ventral tissue. Forelimb and hindlimb function was severely impaired immediately post-injury, but all rats regained the ability to use their hindlimbs for locomotion. Gripping ability was abolished immediately after injury but recovered partially, depending upon the spinal level and severity of the injury. Rats exhibited a loss of sensation in both fore- and hindlimbs that partially recovered, and did not exhibit allodynia. Tract tracing revealed that the main contingent of CST axons in the DC was completely interrupted in all but one animal whereas the dorsolateral CST (dlCST) was partially spared, and dlCST axons gave rise to axons that arborized in the GM caudal to the injury. Our data demonstrate that rats can survive significant bilateral cervical contusion injuries at or below C5 and that forepaw gripping function recovers after mild injuries even when the main component of CST axons in the dorsal column is completely interrupted." @default.
• W1970314102 created "2016-06-24" @default.
• W1970314102 creator A5015954449 @default.
• W1970314102 creator A5049033686 @default.
• W1970314102 creator A5057000646 @default.
• W1970314102 date "2009-11-01" @default.
• W1970314102 modified "2023-10-01" @default.
• W1970314102 title "Bilateral cervical contusion spinal cord injury in rats" @default.
• W1970314102 cites W1569061064 @default.
• W1970314102 cites W1967503662 @default.
• W1970314102 cites W1969993314 @default.
• W1970314102 cites W1973153090 @default.
• W1970314102 cites W1975211350 @default.
• W1970314102 cites W1979757387 @default.
• W1970314102 cites W2004786265 @default.
• W1970314102 cites W2012924135 @default.
• W1970314102 cites W2035970454 @default.
• W1970314102 cites W2036502517 @default.
• W1970314102 cites W2038198950 @default.
• W1970314102 cites W2038275723 @default.
• W1970314102 cites W2039118899 @default.
• W1970314102 cites W2046280925 @default.
• W1970314102 cites W2048952139 @default.
• W1970314102 cites W2056883423 @default.
• W1970314102 cites W2059026830 @default.
• W1970314102 cites W2066106883 @default.
• W1970314102 cites W2067208808 @default.
• W1970314102 cites W2067908390 @default.
• W1970314102 cites W2072992548 @default.
• W1970314102 cites W2076492394 @default.
• W1970314102 cites W2081337741 @default.
• W1970314102 cites W2083894178 @default.
• W1970314102 cites W2084527441 @default.
• W1970314102 cites W2094311325 @default.
• W1970314102 cites W2107445843 @default.
• W1970314102 cites W2112238516 @default.
• W1970314102 cites W2141091196 @default.
• W1970314102 cites W2161627636 @default.
• W1970314102 cites W2171390081 @default.
• W1970314102 doi "https://doi.org/10.1016/j.expneurol.2009.06.012" @default.
• W1970314102 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2761499" @default.
• W1970314102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19559699" @default.
• W1970314102 hasPublicationYear "2009" @default.
• W1970314102 type Work @default.
• W1970314102 sameAs 1970314102 @default.
• W1970314102 citedByCount "86" @default.
• W1970314102 countsByYear W19703141022012 @default.
• W1970314102 countsByYear W19703141022013 @default.
• W1970314102 countsByYear W19703141022014 @default.
• W1970314102 countsByYear W19703141022015 @default.
• W1970314102 countsByYear W19703141022016 @default.
• W1970314102 countsByYear W19703141022017 @default.
• W1970314102 countsByYear W19703141022018 @default.
• W1970314102 countsByYear W19703141022019 @default.
• W1970314102 countsByYear W19703141022020 @default.
• W1970314102 countsByYear W19703141022021 @default.
• W1970314102 countsByYear W19703141022022 @default.
• W1970314102 countsByYear W19703141022023 @default.
• W1970314102 crossrefType "journal-article" @default.
• W1970314102 hasAuthorship W1970314102A5015954449 @default.
• W1970314102 hasAuthorship W1970314102A5049033686 @default.
• W1970314102 hasAuthorship W1970314102A5057000646 @default.
• W1970314102 hasBestOaLocation W19703141022 @default.
• W1970314102 hasConcept C105702510 @default.
• W1970314102 hasConcept C118552586 @default.
• W1970314102 hasConcept C126838900 @default.
• W1970314102 hasConcept C143409427 @default.
• W1970314102 hasConcept C149550507 @default.
• W1970314102 hasConcept C2777368234 @default.
• W1970314102 hasConcept C2778334475 @default.
• W1970314102 hasConcept C2778646069 @default.
• W1970314102 hasConcept C2779530196 @default.
• W1970314102 hasConcept C2779779279 @default.
• W1970314102 hasConcept C2780775167 @default.
• W1970314102 hasConcept C42219234 @default.
• W1970314102 hasConcept C51738704 @default.
• W1970314102 hasConcept C71924100 @default.
• W1970314102 hasConceptScore W1970314102C105702510 @default.
• W1970314102 hasConceptScore W1970314102C118552586 @default.
• W1970314102 hasConceptScore W1970314102C126838900 @default.
• W1970314102 hasConceptScore W1970314102C143409427 @default.
• W1970314102 hasConceptScore W1970314102C149550507 @default.
• W1970314102 hasConceptScore W1970314102C2777368234 @default.
• W1970314102 hasConceptScore W1970314102C2778334475 @default.
• W1970314102 hasConceptScore W1970314102C2778646069 @default.
• W1970314102 hasConceptScore W1970314102C2779530196 @default.
• W1970314102 hasConceptScore W1970314102C2779779279 @default.
• W1970314102 hasConceptScore W1970314102C2780775167 @default.
• W1970314102 hasConceptScore W1970314102C42219234 @default.
• W1970314102 hasConceptScore W1970314102C51738704 @default.
• W1970314102 hasConceptScore W1970314102C71924100 @default.
• W1970314102 hasIssue "1" @default.
• W1970314102 hasLocation W19703141021 @default.
• W1970314102 hasLocation W19703141022 @default.
• W1970314102 hasLocation W19703141023 @default.
• W1970314102 hasLocation W19703141024 @default.
• W1970314102 hasOpenAccess W1970314102 @default.
• W1970314102 hasPrimaryLocation W19703141021 @default.

• next