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• W1970325521 abstract "Potassium channel α-subunits encoded by KCNQ1-5 genes form voltage-dependent channels (KV7), modulated by KCNE1-5 encoded accessory proteins. The aim was to determine KCNQ and KCNE mRNA expression and assess protein expression/localisation of the KCNQ3 and KCNE5 isoforms in first trimester placental tissue. Placentae were obtained from women undergoing elective surgical termination of pregnancy (TOP) at ≤ 10 weeks' (early TOP) and >10 weeks' (mid TOP) gestations. KCNQ1-5 expression was unchanged during the first trimester. KCNE5 expression increased in mid TOP vs. early TOP samples (P = 0.022). This novel study reports mRNA and protein expression of KV7 channels in first trimester placentae." @default.
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• W1970325521 date "2014-05-01" @default.
• W1970325521 modified "2023-10-18" @default.
• W1970325521 title "Expression of voltage-dependent potassium channels in first trimester human placentae" @default.
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• W1970325521 doi "https://doi.org/10.1016/j.placenta.2014.02.008" @default.
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