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- W1970404833 abstract "HLA-DO is a non-classical MHC class II molecule presumed to play a specialized role in the antigen processing pathway. We have modeled the HLA-DOβ-chain and found its overall structure compatible with the one of DRβ. Functional studies further highlighted the similarity between these β-chains of the class II family of proteins. Indeed, a mixed heterodimer composed of the DRα and a chimeric DOβ-chains presented bacterial superantigens to T cells and was shown to interact with CD4. The implications of such structural conservation for the in vivo functions of HLA-DO are discussed." @default.
- W1970404833 created "2016-06-24" @default.
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- W1970404833 date "1998-08-01" @default.
- W1970404833 modified "2023-09-27" @default.
- W1970404833 title "Clinical outcome of hypogammaglobulinemic patients following outbreak of hepatitis C infection: 4 year follow-up" @default.
- W1970404833 doi "https://doi.org/10.1016/s0161-5890(98)90496-5" @default.
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