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• W1970430829 abstract "This case study demonstrates that patients with NCCP can be subclassified on the basis of sensory responsiveness and neurophysiologic profiles. This approach identifies specific abnormalities within the CNS processing of esophageal sensation in individual patients, allowing us to objectively differentiate those with sensitized esophageal afferents from those that are hypervigilant to esophageal sensations. The importance of this approach is to underline that NCCP comprises a heterogeneous group of patients. and only when we have defined the phenotype of this condition and identified groups of patients with specific CNS abnormalities will it be possible to perform clinical studies aimed at answering specific hypotheses. The development of a comprehensive pathophysiologic model that identifies the specific causes of symptoms in patients with esophageal hypersensitivity will allow the future management strategies of these patients to be targeted more specifically and efficiently. This will have great benefits to patients'well-being and health care use." @default.
• W1970430829 created "2016-06-24" @default.
• W1970430829 creator A5054250912 @default.
• W1970430829 creator A5062693472 @default.
• W1970430829 date "2004-03-01" @default.
• W1970430829 modified "2023-10-15" @default.
• W1970430829 title "Brain processing of esophageal sensation in health and disease" @default.
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• W1970430829 doi "https://doi.org/10.1016/s0889-8553(03)00132-8" @default.
• W1970430829 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15062439" @default.
• W1970430829 hasPublicationYear "2004" @default.
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