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- W1970431737 abstract "To investigate the effect of transcatheter arterial embolization (TAE) or lipiodolization (Lip) on additional tumoricidal activities and the immune system, we studied the serum tumor necrosis factor (TNF) activity before and after either TAE or Lip in patients with hepatocellular carcinoma (HCC). No significant differences in the serum basal TNF activities were observed before TAE or Lip among either the normal controls, patients with cirrhosis (LC) or patients with HCC. The serum TNF activities increased in four of 15 patients with HCC after the treatment. On the other hand, the TNF production of peripheral blood mononuclear cells (PBMCs) in five patients with HCC increased from 9.0 ± 3.8 U/ml to 18.8 ± 8.7 U/ml (P < 0.05) after the treatment. It is well known that the anti-tumor effect of TAE or Lip is based mainly on ischemia and the effect of anti-cancer drugs. In the present study, the activation of TNF production by TAE or Lip was also suggested to cause an anti-tumor effect." @default.
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- W1970431737 date "1994-02-15" @default.
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- W1970431737 title "Transcatheter arterial embolization or lipiodolization raises the production of tumor necrosis factor activity in patients with hepatocellular carcinoma" @default.
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- W1970431737 doi "https://doi.org/10.1016/0928-4346(94)90015-9" @default.
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