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- W1970439500 abstract "Introduction: To investigate the value of MR Imaging with a contrast enhanced 2D-balanced-FFE (True-FISP) sequence in comparison to standard procedures and conventional MR-sequences in the evaluation of children with suspected chronic inflammatory bowel disease (IBD). Methods: 30 children, aged 7–18 years, with suspected IBD underwent MR-Imaging on a 1.5T-scanner (Philips ACS-NT, Best, Netherlands) in addition to standard diagnostic workup including endoscopy and conventional x-ray enteroclysis. 1 hour after 1l of 2.5% mannitol-solution was given orally, MR imaging was performed using coronal HASTE-M2D, coronal fat-suppressed T2-TSE, axial dynamic T1-weighted GE-sequences before and after i.v.-contrast and a 2D-balanced-FFE-sequence (True-FISP) before and after i.v.-contrast material injection in coronal and axial planes. The MR-images were evaluated by three experienced radiologists regarding the sensitivity of each sequence in the detection of intestinal abnormalities as well as the delineation of thickening of the small-bowel wall and the ileocecal valve. The image findings were correlated with the endoscopic and histologic findings and with conventional x-ray enteroclysis. Furthermore, the image quality was assessed regarding the different tissue-contrasts and the susceptibility to artifacts. Results: The sensitivity in the detection of small-bowel abnormalities was found to be 97% with use of the True-FISP-sequence and 88–95% with use of the other sequences. The True-FISP sequence revealed the best soft-tissue differentiation in comparison to all other performed MR-sequences. The delineation of the bowel wall thickening, the ileocecal valve and of extraintestinal inflammatory reaction was significantly improved applying the True-FISP-sequence. The difference between pre-and post i.v.-contrast-enhanced True-FISP-sequences was not significant. The True-FISP proved to be a quick and stable sequence not sensitive to artifacts. Conclusion: MR Imaging with the use of the True-FISP-sequence is a powerful tool in the diagnosis and follow up of children with IBD. Compared to conventional MR-sequences, the True-FISP sequence significantly improves the assessment of inflammatory changes regarding delineation of bowel wall thickening and periintestinal inflammation. It will replace conventional x-ray investigations for this diagnostic approach." @default.
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- W1970439500 date "2004-06-01" @default.
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- W1970439500 title "P0622 MR IMAGING OF THE SMALL BOWEL IN CHILDREN WITH CHRONIC INFLAMMATORY BOWEL DISEASE" @default.
- W1970439500 doi "https://doi.org/10.1097/00005176-200406001-00746" @default.
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