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- W1970444587 abstract "Bone has always been considered a target organ for neoplastic disorder. This review analyzed the close interaction between bone microenvironment and paraproteinemias.Paraproteinemias are a group of disorders characterized by the presence of a monoclonal protein measured in the blood or urine. Paraproteinemias include nonmalignant B cell disorders such as monoclonal gammopathy of undetermined significance and malignant diseases as multiple myeloma. All these conditions are characterized by increased risk of osteoporosis/osteopenia, and in the setting of multiple myeloma can manifest with osteolytic pattern.This review focuses on the biological aspects of paraproteinemia and bone disease, and indicates possible new therapeutic interventions." @default.
- W1970444587 created "2016-06-24" @default.
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- W1970444587 date "2010-09-01" @default.
- W1970444587 modified "2023-09-25" @default.
- W1970444587 title "Bone and paraproteinemias" @default.
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- W1970444587 doi "https://doi.org/10.1097/spc.0b013e32833d3011" @default.
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