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- W1970451392 abstract "We have investigated the effect of HGF in vivo and in vitro in MDS using a recently developed FCM assay involving the simultaneous measurement of cell surface antigens, DNA content, and BrdUrd or IodUrd incorporation. This allows for the determination of the dynamic cell kinetic parameters: LI, T(s), and T(pot) and we observed that in vitro HGF stimulation resulted in a significant decrease in mean T(pot) values from 6.6 to 3.5 days. Importantly, we demonstrated that in vivo GM-CSF administration to patients with RAEB resulted in a shortening of T(pot) within the 2 first weeks of GM-CSF treatment." @default.
- W1970451392 created "2016-06-24" @default.
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- W1970451392 date "2000-12-01" @default.
- W1970451392 modified "2023-09-28" @default.
- W1970451392 title "Dynamic cell cycle kinetics in vitro and in vivo in myelodysplastic syndromes with special reference to the influence of hematopoietic growth factors" @default.
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- W1970451392 doi "https://doi.org/10.1016/s0145-2126(00)00080-1" @default.
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