Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970488266> ?p ?o ?g. }
- W1970488266 endingPage "444" @default.
- W1970488266 startingPage "437" @default.
- W1970488266 abstract "Major depressive disorder (MDD) is associated with dysfunction of the emotional circuitry in the brain. Psychotherapy and antidepressant treatment both aid in modulating this dysfunction, albeit probably through different mechanisms. A plausible “top-down” emotional regulation mechanism for psychotherapy has been described in previous studies, but the underlying findings are still contradictory. A total of 23 MDD patients and 20 healthy controls were enrolled. The early neural effects within 5 weeks of guided imagery—a psychotherapeutic method for treating depression—were assessed through resting-state functional magnetic resonance imaging using the regional homogeneity analytical method. At baseline, regional homogeneity was reduced in cortical regions and increased in limbic areas in the pre-treatment scans of MDD patients as compared to controls. After 5 weeks of guided imagery therapy, regional homogeneity in the ventromedial prefrontal cortex and the anterior cingulate gyrus both increased. Higher pre-treatment regional homogeneity in the dorsal anterior cingulate gyrus was positively correlated with an improved response to guided imagery therapy. The changes in regional homogeneity induced by guided imagery therapy demonstrate that this method of psychotherapy takes effect through a “top-down” mechanism. Future studies comparing various psychotherapeutic methodologies across multiple time points in the treatment course should yield more valuable insights on this topic." @default.
- W1970488266 created "2016-06-24" @default.
- W1970488266 creator A5012841304 @default.
- W1970488266 creator A5020746135 @default.
- W1970488266 creator A5024524782 @default.
- W1970488266 creator A5038851564 @default.
- W1970488266 creator A5047263000 @default.
- W1970488266 creator A5047728461 @default.
- W1970488266 creator A5050393004 @default.
- W1970488266 creator A5064222660 @default.
- W1970488266 date "2014-12-01" @default.
- W1970488266 modified "2023-10-01" @default.
- W1970488266 title "Early brain changes associated with psychotherapy in major depressive disorder revealed by resting-state fMRI: Evidence for the top-down regulation theory" @default.
- W1970488266 cites W1897465408 @default.
- W1970488266 cites W1963700723 @default.
- W1970488266 cites W1968837585 @default.
- W1970488266 cites W1969032152 @default.
- W1970488266 cites W1969708539 @default.
- W1970488266 cites W1972717007 @default.
- W1970488266 cites W1975430526 @default.
- W1970488266 cites W1976073163 @default.
- W1970488266 cites W1976074659 @default.
- W1970488266 cites W1982516524 @default.
- W1970488266 cites W1985337875 @default.
- W1970488266 cites W1986779034 @default.
- W1970488266 cites W1993274235 @default.
- W1970488266 cites W2006624654 @default.
- W1970488266 cites W2007213925 @default.
- W1970488266 cites W2009828262 @default.
- W1970488266 cites W2014389740 @default.
- W1970488266 cites W2018342377 @default.
- W1970488266 cites W2019151922 @default.
- W1970488266 cites W2022328515 @default.
- W1970488266 cites W2022942602 @default.
- W1970488266 cites W2025147307 @default.
- W1970488266 cites W2026236511 @default.
- W1970488266 cites W2027721376 @default.
- W1970488266 cites W2028159510 @default.
- W1970488266 cites W2029286913 @default.
- W1970488266 cites W2035520183 @default.
- W1970488266 cites W2048087221 @default.
- W1970488266 cites W2048593992 @default.
- W1970488266 cites W2053126345 @default.
- W1970488266 cites W2061759744 @default.
- W1970488266 cites W2064625200 @default.
- W1970488266 cites W2069307582 @default.
- W1970488266 cites W2073602738 @default.
- W1970488266 cites W2077666608 @default.
- W1970488266 cites W2087967429 @default.
- W1970488266 cites W2094608167 @default.
- W1970488266 cites W2095438393 @default.
- W1970488266 cites W2098818989 @default.
- W1970488266 cites W2099527308 @default.
- W1970488266 cites W2105679606 @default.
- W1970488266 cites W2106089606 @default.
- W1970488266 cites W2115323382 @default.
- W1970488266 cites W2117994084 @default.
- W1970488266 cites W2122384242 @default.
- W1970488266 cites W2124250881 @default.
- W1970488266 cites W2131976593 @default.
- W1970488266 cites W2137066073 @default.
- W1970488266 cites W2137296158 @default.
- W1970488266 cites W2140852353 @default.
- W1970488266 cites W2142875089 @default.
- W1970488266 cites W2145702255 @default.
- W1970488266 cites W2150215146 @default.
- W1970488266 cites W2152141502 @default.
- W1970488266 cites W2153566421 @default.
- W1970488266 cites W2154112437 @default.
- W1970488266 cites W2156717193 @default.
- W1970488266 cites W2156809536 @default.
- W1970488266 cites W2156923987 @default.
- W1970488266 cites W2162541816 @default.
- W1970488266 cites W2162839373 @default.
- W1970488266 cites W2165648119 @default.
- W1970488266 cites W2166320364 @default.
- W1970488266 cites W2171752682 @default.
- W1970488266 cites W4239347603 @default.
- W1970488266 cites W4253468745 @default.
- W1970488266 cites W57359236 @default.
- W1970488266 doi "https://doi.org/10.1016/j.ijpsycho.2014.10.011" @default.
- W1970488266 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25448375" @default.
- W1970488266 hasPublicationYear "2014" @default.
- W1970488266 type Work @default.
- W1970488266 sameAs 1970488266 @default.
- W1970488266 citedByCount "27" @default.
- W1970488266 countsByYear W19704882662015 @default.
- W1970488266 countsByYear W19704882662016 @default.
- W1970488266 countsByYear W19704882662017 @default.
- W1970488266 countsByYear W19704882662018 @default.
- W1970488266 countsByYear W19704882662019 @default.
- W1970488266 countsByYear W19704882662020 @default.
- W1970488266 countsByYear W19704882662021 @default.
- W1970488266 countsByYear W19704882662022 @default.
- W1970488266 countsByYear W19704882662023 @default.
- W1970488266 crossrefType "journal-article" @default.
- W1970488266 hasAuthorship W1970488266A5012841304 @default.
- W1970488266 hasAuthorship W1970488266A5020746135 @default.