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• W1970497573 abstract "The ability to utilize oxygen has been shown to affect a wide variety of physiological factors often considered beneficial for survival. As the ability to learn can be seen as one of the core factors of survival in mammals, we studied whether selective breeding for endurance running, an indication of aerobic capacity, also has an effect on learning. Rats selectively bred over 23 generations for their ability to perform forced treadmill running were trained in an appetitively motivated discrimination-reversal classical conditioning task, an alternating T-maze task followed by a rule change (from a shift-win to stay-win rule) and motor learning task. In the discrimination-reversal and T-maze tasks, the high-capacity runner (HCR) rats outperformed the low-capacity runner (LCR) rats, most notably in the phases requiring flexible cognition. In the Rotarod (motor-learning) task, the HCR animals were overall more agile but learned at a similar rate with the LCR group as a function of training. We conclude that the intrinsic ability to utilize oxygen is associated especially with tasks requiring plasticity of the brain structures implicated in flexible cognition." @default.
• W1970497573 created "2016-06-24" @default.
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• W1970497573 date "2012-05-01" @default.
• W1970497573 modified "2023-10-18" @default.
• W1970497573 title "Selective breeding for endurance running capacity affects cognitive but not motor learning in rats" @default.
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• W1970497573 doi "https://doi.org/10.1016/j.physbeh.2012.01.011" @default.
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