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- W1970542893 abstract "Abstract The expression of genes potentially involved in paralytic shellfish toxin (PST) biosynthesis was quantified during cell division of the dinoflagellate Alexandrium catenella. Basic precursors of the neurotoxic PST molecule(s), such as S-adenosylmethionine (SAM), have been hypothesised, but no genes coding for PST production have been definitively identified in dinoflagellates. Sam encodes the enzyme SAM synthetase and two other candidate PST genes S-adenosylhomocysteine hydrolase (Sahh) and methionine aminopeptidase (Map) have been previously identified in the closely related PST producing dinoflagellate Alexandrium fundyense. PST production and expression of Sam, Sahh and Map were examined concurrently during cell division in A. catenella. The PST profile of A. catenella was dominated by C2 (30–37 mol%), GTX5 (12–19 mol%) and GTX6 (27–33 mol%) and was constant over the cell cycle. However, the net cellular PST production rate varied over the cell cycle and was highest (127 fmol cell−1 h−1) during..." @default.
- W1970542893 created "2016-06-24" @default.
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- W1970542893 date "2007-11-01" @default.
- W1970542893 modified "2023-09-24" @default.
- W1970542893 title "Sam, Sahh and Map gene expression during cell division and paralytic shellfish toxin production of Alexandrium catenella (Dinophyceae)" @default.
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- W1970542893 doi "https://doi.org/10.2216/07-25.1" @default.
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