FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970553920> ?p ?o ?g. }

• W1970553920 endingPage "155" @default.
• W1970553920 startingPage "148" @default.
• W1970553920 abstract "The dark discoloration of globus pallidus and substantia nigra pars reticularis in the Hallervorden-Spatz syndrome is due to the accumulation of iron. Routine iron stains detect the metal mostly in microglia and macrophages, but scattered neurons are also reactive. Axonal spheroids are characteristic of the disease, and many of these expansions give a positive iron reaction. Globus pallidus and substantia nigra are normally rich in iron, and additional storage of the metal has often been considered the essential factor in the pathogenesis of Hallervorden-Spatz syndrome. However, other equally iron-rich structures, such as the red nucleus and the dentate nucleus, remain unaffected. In normal globus pallidus and substantia nigra pars reticularis, double-label immunofluorescence microscopy of ferritin, as an indirect marker of cellular iron localization, and phosphorylated neurofilament protein reveal close proximity of ferritin-reactive microglial and oligodendroglial processes to tightly packed axons. It is proposed that a primary axonal disorder allows the seepage of iron into the axoplasm. Iron may contribute to the axonal disease, but accumulation of the metal probably should be viewed as an epiphenomenon. Pallidal and nigral iron excess is not unique to Hallervorden-Spatz syndrome, and some previously reported postmortem examinations may actually represent pallidonigroluysian atrophy." @default.
• W1970553920 created "2016-06-24" @default.
• W1970553920 creator A5062004674 @default.
• W1970553920 creator A5088009058 @default.
• W1970553920 date "2001-08-01" @default.
• W1970553920 modified "2023-10-10" @default.
• W1970553920 title "Iron in the Hallervorden-Spatz syndrome" @default.
• W1970553920 cites W1513908444 @default.
• W1970553920 cites W1568628619 @default.
• W1970553920 cites W1968043158 @default.
• W1970553920 cites W1972509721 @default.
• W1970553920 cites W1973077436 @default.
• W1970553920 cites W1974804543 @default.
• W1970553920 cites W1980920477 @default.
• W1970553920 cites W1981835221 @default.
• W1970553920 cites W1990409762 @default.
• W1970553920 cites W1992374322 @default.
• W1970553920 cites W1998768593 @default.
• W1970553920 cites W2004572853 @default.
• W1970553920 cites W2019048519 @default.
• W1970553920 cites W2020053586 @default.
• W1970553920 cites W2028415314 @default.
• W1970553920 cites W2031884599 @default.
• W1970553920 cites W2037259851 @default.
• W1970553920 cites W2040781504 @default.
• W1970553920 cites W2042668203 @default.
• W1970553920 cites W2043029020 @default.
• W1970553920 cites W2046260941 @default.
• W1970553920 cites W2051895212 @default.
• W1970553920 cites W2056360572 @default.
• W1970553920 cites W2069933213 @default.
• W1970553920 cites W2070771278 @default.
• W1970553920 cites W2074700700 @default.
• W1970553920 cites W2077259833 @default.
• W1970553920 cites W2082534696 @default.
• W1970553920 cites W2089676648 @default.
• W1970553920 cites W2144350881 @default.
• W1970553920 cites W2164577948 @default.
• W1970553920 cites W2165732672 @default.
• W1970553920 cites W265358815 @default.
• W1970553920 cites W2977427556 @default.
• W1970553920 cites W3143544522 @default.
• W1970553920 doi "https://doi.org/10.1016/s0887-8994(01)00269-7" @default.
• W1970553920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11551745" @default.
• W1970553920 hasPublicationYear "2001" @default.
• W1970553920 type Work @default.
• W1970553920 sameAs 1970553920 @default.
• W1970553920 citedByCount "49" @default.
• W1970553920 countsByYear W19705539202012 @default.
• W1970553920 countsByYear W19705539202013 @default.
• W1970553920 countsByYear W19705539202016 @default.
• W1970553920 countsByYear W19705539202017 @default.
• W1970553920 countsByYear W19705539202018 @default.
• W1970553920 countsByYear W19705539202023 @default.
• W1970553920 crossrefType "journal-article" @default.
• W1970553920 hasAuthorship W1970553920A5062004674 @default.
• W1970553920 hasAuthorship W1970553920A5088009058 @default.
• W1970553920 hasConcept C142724271 @default.
• W1970553920 hasConcept C169760540 @default.
• W1970553920 hasConcept C185592680 @default.
• W1970553920 hasConcept C2777830160 @default.
• W1970553920 hasConcept C2778187257 @default.
• W1970553920 hasConcept C2778319317 @default.
• W1970553920 hasConcept C2779134260 @default.
• W1970553920 hasConcept C2779384463 @default.
• W1970553920 hasConcept C2779652256 @default.
• W1970553920 hasConcept C2779734285 @default.
• W1970553920 hasConcept C2780278869 @default.
• W1970553920 hasConcept C2780723820 @default.
• W1970553920 hasConcept C2780938664 @default.
• W1970553920 hasConcept C529278444 @default.
• W1970553920 hasConcept C71924100 @default.
• W1970553920 hasConcept C86803240 @default.
• W1970553920 hasConceptScore W1970553920C142724271 @default.
• W1970553920 hasConceptScore W1970553920C169760540 @default.
• W1970553920 hasConceptScore W1970553920C185592680 @default.
• W1970553920 hasConceptScore W1970553920C2777830160 @default.
• W1970553920 hasConceptScore W1970553920C2778187257 @default.
• W1970553920 hasConceptScore W1970553920C2778319317 @default.
• W1970553920 hasConceptScore W1970553920C2779134260 @default.
• W1970553920 hasConceptScore W1970553920C2779384463 @default.
• W1970553920 hasConceptScore W1970553920C2779652256 @default.
• W1970553920 hasConceptScore W1970553920C2779734285 @default.
• W1970553920 hasConceptScore W1970553920C2780278869 @default.
• W1970553920 hasConceptScore W1970553920C2780723820 @default.
• W1970553920 hasConceptScore W1970553920C2780938664 @default.
• W1970553920 hasConceptScore W1970553920C529278444 @default.
• W1970553920 hasConceptScore W1970553920C71924100 @default.
• W1970553920 hasConceptScore W1970553920C86803240 @default.
• W1970553920 hasIssue "2" @default.
• W1970553920 hasLocation W19705539201 @default.
• W1970553920 hasLocation W19705539202 @default.
• W1970553920 hasOpenAccess W1970553920 @default.
• W1970553920 hasPrimaryLocation W19705539201 @default.
• W1970553920 hasRelatedWork W1964442944 @default.
• W1970553920 hasRelatedWork W2013028055 @default.
• W1970553920 hasRelatedWork W2026575585 @default.
• W1970553920 hasRelatedWork W2056945056 @default.

• next