FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970561010> ?p ?o ?g. }

• W1970561010 endingPage "546" @default.
• W1970561010 startingPage "537" @default.
• W1970561010 abstract "The renal site of the natriuretic effect of human, atrial natriuretic peptide (hANP) was studied using clearance techniques in eight salt-loaded normal volunteers undergoing maximal water diuresis. Lithium was used as a marker of proximal sodium reabsorption. According to a two-way, single blind, crossover design, hANP (Met12-(3-28)-eicosahexapeptide, (2 micrograms/min) or its vehicle (Ve) were infused for two hours, followed by a two-hour recovery period. Blood pressure, heart rate and insulin clearance remained unchanged. During hANP infusion, the filtration fraction increased slightly from 19.6 to 24.3% (P less than 0.001), fractional water excretion rose transiently at the beginning of the infusion. Fractional excretion of sodium increased markedly from 2.2% to 7.4% (P less than 0.001) but remained unchanged with Ve. ANP increased fractional excretion of lithium slightly from 46 to 58% (P less than 0.01), while it remained stable at 47% during Ve. The distal tubular rejection fraction of sodium calculated from sodium and lithium clearances rose markedly from 4.7 to 13% (P less than 0.001) and returned to 6.2% at the end of the recovery period. Thus, under salt loading and water diuresis conditions, hANP infusion did not alter GFR, but reduced proximal reabsorption of sodium, and markedly enhanced the fraction of sodium escaping distal tubular reabsorption, suggesting that hANP-induced natriuresis is due, for an important part, to inhibition of sodium reabsorption in the distal nephron." @default.
• W1970561010 created "2016-06-24" @default.
• W1970561010 creator A5003444918 @default.
• W1970561010 creator A5004569891 @default.
• W1970561010 creator A5008538678 @default.
• W1970561010 creator A5029428482 @default.
• W1970561010 creator A5032738255 @default.
• W1970561010 creator A5036167932 @default.
• W1970561010 creator A5040889620 @default.
• W1970561010 creator A5072851099 @default.
• W1970561010 date "1987-10-01" @default.
• W1970561010 modified "2023-10-15" @default.
• W1970561010 title "Site of the action of a synthetic atrial natriuretic peptide evaluated in humans" @default.
• W1970561010 cites W1517020542 @default.
• W1970561010 cites W1838159917 @default.
• W1970561010 cites W1964404358 @default.
• W1970561010 cites W1977250235 @default.
• W1970561010 cites W1982550769 @default.
• W1970561010 cites W1985536252 @default.
• W1970561010 cites W1986061670 @default.
• W1970561010 cites W1988523436 @default.
• W1970561010 cites W1992982390 @default.
• W1970561010 cites W1998089737 @default.
• W1970561010 cites W2005257617 @default.
• W1970561010 cites W2008448587 @default.
• W1970561010 cites W2015283139 @default.
• W1970561010 cites W2015937443 @default.
• W1970561010 cites W2023758236 @default.
• W1970561010 cites W2026445365 @default.
• W1970561010 cites W2035480425 @default.
• W1970561010 cites W2043733090 @default.
• W1970561010 cites W2049984676 @default.
• W1970561010 cites W2052097767 @default.
• W1970561010 cites W2052394069 @default.
• W1970561010 cites W2065816057 @default.
• W1970561010 cites W2066774400 @default.
• W1970561010 cites W2068631477 @default.
• W1970561010 cites W2075507006 @default.
• W1970561010 cites W2076734878 @default.
• W1970561010 cites W2092505871 @default.
• W1970561010 cites W2093175759 @default.
• W1970561010 cites W2096656813 @default.
• W1970561010 cites W2099601233 @default.
• W1970561010 cites W2106312406 @default.
• W1970561010 cites W2111110375 @default.
• W1970561010 cites W2117417511 @default.
• W1970561010 cites W2127415246 @default.
• W1970561010 cites W2141718346 @default.
• W1970561010 cites W2150120426 @default.
• W1970561010 cites W2273737528 @default.
• W1970561010 cites W2304420852 @default.
• W1970561010 cites W2316502914 @default.
• W1970561010 cites W2400131153 @default.
• W1970561010 cites W2406448749 @default.
• W1970561010 cites W2412173019 @default.
• W1970561010 cites W2412909422 @default.
• W1970561010 cites W2414449194 @default.
• W1970561010 cites W2429755653 @default.
• W1970561010 doi "https://doi.org/10.1038/ki.1987.242" @default.
• W1970561010 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2963166" @default.
• W1970561010 hasPublicationYear "1987" @default.
• W1970561010 type Work @default.
• W1970561010 sameAs 1970561010 @default.
• W1970561010 citedByCount "49" @default.
• W1970561010 countsByYear W19705610102017 @default.
• W1970561010 countsByYear W19705610102018 @default.
• W1970561010 crossrefType "journal-article" @default.
• W1970561010 hasAuthorship W1970561010A5003444918 @default.
• W1970561010 hasAuthorship W1970561010A5004569891 @default.
• W1970561010 hasAuthorship W1970561010A5008538678 @default.
• W1970561010 hasAuthorship W1970561010A5029428482 @default.
• W1970561010 hasAuthorship W1970561010A5032738255 @default.
• W1970561010 hasAuthorship W1970561010A5036167932 @default.
• W1970561010 hasAuthorship W1970561010A5040889620 @default.
• W1970561010 hasAuthorship W1970561010A5072851099 @default.
• W1970561010 hasBestOaLocation W19705610101 @default.
• W1970561010 hasConcept C10146269 @default.
• W1970561010 hasConcept C119584498 @default.
• W1970561010 hasConcept C126322002 @default.
• W1970561010 hasConcept C134018914 @default.
• W1970561010 hasConcept C142225936 @default.
• W1970561010 hasConcept C159641895 @default.
• W1970561010 hasConcept C161457703 @default.
• W1970561010 hasConcept C174459258 @default.
• W1970561010 hasConcept C178790620 @default.
• W1970561010 hasConcept C185592680 @default.
• W1970561010 hasConcept C2778069365 @default.
• W1970561010 hasConcept C2779547328 @default.
• W1970561010 hasConcept C2780091579 @default.
• W1970561010 hasConcept C2780343553 @default.
• W1970561010 hasConcept C2781231759 @default.
• W1970561010 hasConcept C537181965 @default.
• W1970561010 hasConcept C56906281 @default.
• W1970561010 hasConcept C57476199 @default.
• W1970561010 hasConcept C71924100 @default.
• W1970561010 hasConceptScore W1970561010C10146269 @default.
• W1970561010 hasConceptScore W1970561010C119584498 @default.
• W1970561010 hasConceptScore W1970561010C126322002 @default.

• next