FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970596537> ?p ?o ?g. }

• W1970596537 endingPage "1546" @default.
• W1970596537 startingPage "1540" @default.
• W1970596537 abstract "<b>BACKGROUND AND PURPOSE:</b> Our aim was to retrospectively investigate the prognostic significance of the degree of contrast enhancement in tumors and its additional value in previously considered MR imaging parameters with regard to local control of laryngeal cancer treated with radiation therapy (RT) alone. <b>MATERIALS AND METHODS:</b> Pretreatment MR images of 64 consecutive patients (54 men and 10 women, 43–80 years of age) with supraglottic and glottic cancer were retrospectively reviewed on clinical and previously considered MR imaging parameters such as tumor involvement of specific laryngeal anatomic subsites, including laryngeal cartilages, tumor volume, extralaryngeal tumor spread, and, in addition, the degree of contrast enhancement. Clinical and MR imaging parameters were associated with regard to local control at 2 years by using the Cox regression model. “Local control” was defined as absence of primary tumor recurrence. <b>RESULTS:</b> When using a threshold of the mean average contrast enhancement of 77%, the 2-year local control rate in the groups of patients with a degree of enhancement below and above this threshold was 57% and 70%, respectively (<i>P</i>=.3). Enhancement of tumor tissue in pre-epiglottic space (PES) was low, most probably due to its adipose tissue and poor vascular content, whereas tumor tissue involving paraglottic space (PGS) did enhance. Results of multivariate analysis indicated that the degree of contrast enhancement yielded the prognostic information (<i>P</i>=.07) with 2 independent prognostic factors: primary tumor volume (<i>P</i>=.007) and subglottic extension (<i>P</i>=.002) with regard to local control. Using these previously mentioned 3 MR imaging parameters as potential risk factors, we defined 4 categories, resulting in the following local control rates respectively: 90% for the group without risk factors, 73% for the group with 1, 60% for the group with 2, and finally 0% for the group with 3 risk factors, which was significantly lower than the rates in previous risk groups (<i>P</i> < .001). <b>CONCLUSION:</b> PES has a lower degree of contrast enhancement than the PGS and may correlate with the worse outcome. Including a low degree of contrast enhancement as a parameter to primary tumor volume and subglottic extension may increase the predictive value of MR imaging for local outcome and may be helpful to identify a subset of patients whose tumors all recurred locally within 2 years after primary RT." @default.
• W1970596537 created "2016-06-24" @default.
• W1970596537 creator A5002522655 @default.
• W1970596537 creator A5019926739 @default.
• W1970596537 creator A5058032050 @default.
• W1970596537 creator A5064017487 @default.
• W1970596537 creator A5066894573 @default.
• W1970596537 creator A5070012126 @default.
• W1970596537 creator A5086717130 @default.
• W1970596537 date "2007-09-01" @default.
• W1970596537 modified "2023-10-12" @default.
• W1970596537 title "Has the Degree of Contrast Enhancement with MR Imaging in Laryngeal Carcinoma Added Value to Anatomic Parameters Regarding Prediction of Response to Radiation Therapy?" @default.
• W1970596537 cites W1604648525 @default.
• W1970596537 cites W1967670124 @default.
• W1970596537 cites W1977793938 @default.
• W1970596537 cites W1978413349 @default.
• W1970596537 cites W1978996858 @default.
• W1970596537 cites W1987065233 @default.
• W1970596537 cites W1990832359 @default.
• W1970596537 cites W1993683062 @default.
• W1970596537 cites W2005361380 @default.
• W1970596537 cites W2025441414 @default.
• W1970596537 cites W2039202334 @default.
• W1970596537 cites W2039530430 @default.
• W1970596537 cites W2043507448 @default.
• W1970596537 cites W2049088667 @default.
• W1970596537 cites W2052489624 @default.
• W1970596537 cites W2093999024 @default.
• W1970596537 cites W2100961085 @default.
• W1970596537 cites W2104872649 @default.
• W1970596537 cites W2147737847 @default.
• W1970596537 cites W2157607856 @default.
• W1970596537 doi "https://doi.org/10.3174/ajnr.a0599" @default.
• W1970596537 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8134409" @default.
• W1970596537 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17846208" @default.
• W1970596537 hasPublicationYear "2007" @default.
• W1970596537 type Work @default.
• W1970596537 sameAs 1970596537 @default.
• W1970596537 citedByCount "6" @default.
• W1970596537 countsByYear W19705965372013 @default.
• W1970596537 countsByYear W19705965372014 @default.
• W1970596537 countsByYear W19705965372017 @default.
• W1970596537 countsByYear W19705965372021 @default.
• W1970596537 crossrefType "journal-article" @default.
• W1970596537 hasAuthorship W1970596537A5002522655 @default.
• W1970596537 hasAuthorship W1970596537A5019926739 @default.
• W1970596537 hasAuthorship W1970596537A5058032050 @default.
• W1970596537 hasAuthorship W1970596537A5064017487 @default.
• W1970596537 hasAuthorship W1970596537A5066894573 @default.
• W1970596537 hasAuthorship W1970596537A5070012126 @default.
• W1970596537 hasAuthorship W1970596537A5086717130 @default.
• W1970596537 hasBestOaLocation W19705965371 @default.
• W1970596537 hasConcept C121608353 @default.
• W1970596537 hasConcept C126322002 @default.
• W1970596537 hasConcept C126838900 @default.
• W1970596537 hasConcept C141071460 @default.
• W1970596537 hasConcept C142724271 @default.
• W1970596537 hasConcept C2777546739 @default.
• W1970596537 hasConcept C2780474809 @default.
• W1970596537 hasConcept C2989005 @default.
• W1970596537 hasConcept C50382708 @default.
• W1970596537 hasConcept C509974204 @default.
• W1970596537 hasConcept C71924100 @default.
• W1970596537 hasConceptScore W1970596537C121608353 @default.
• W1970596537 hasConceptScore W1970596537C126322002 @default.
• W1970596537 hasConceptScore W1970596537C126838900 @default.
• W1970596537 hasConceptScore W1970596537C141071460 @default.
• W1970596537 hasConceptScore W1970596537C142724271 @default.
• W1970596537 hasConceptScore W1970596537C2777546739 @default.
• W1970596537 hasConceptScore W1970596537C2780474809 @default.
• W1970596537 hasConceptScore W1970596537C2989005 @default.
• W1970596537 hasConceptScore W1970596537C50382708 @default.
• W1970596537 hasConceptScore W1970596537C509974204 @default.
• W1970596537 hasConceptScore W1970596537C71924100 @default.
• W1970596537 hasIssue "8" @default.
• W1970596537 hasLocation W19705965371 @default.
• W1970596537 hasLocation W19705965372 @default.
• W1970596537 hasLocation W19705965373 @default.
• W1970596537 hasOpenAccess W1970596537 @default.
• W1970596537 hasPrimaryLocation W19705965371 @default.
• W1970596537 hasRelatedWork W2040364978 @default.
• W1970596537 hasRelatedWork W2044504567 @default.
• W1970596537 hasRelatedWork W2045296221 @default.
• W1970596537 hasRelatedWork W2121960536 @default.
• W1970596537 hasRelatedWork W2277413675 @default.
• W1970596537 hasRelatedWork W2384708512 @default.
• W1970596537 hasRelatedWork W2413799329 @default.
• W1970596537 hasRelatedWork W2416811784 @default.
• W1970596537 hasRelatedWork W2525179853 @default.
• W1970596537 hasRelatedWork W2528235162 @default.
• W1970596537 hasVolume "28" @default.
• W1970596537 isParatext "false" @default.
• W1970596537 isRetracted "false" @default.
• W1970596537 magId "1970596537" @default.
• W1970596537 workType "article" @default.