FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970642677> ?p ?o ?g. }

• W1970642677 endingPage "80" @default.
• W1970642677 startingPage "67" @default.
• W1970642677 abstract "Resveratrol (Res) displays potent anti-oxidant activity and is a selective estrogen receptor modulator. The aim of the present study is to investigate whether Res consumption protects ovariectomized (OVX) rats chronically treated with d-galactose (d-gal) from developing memory decline and whether Res administration decreases pathological changes in the endometrium and lumen of the uterus compared with estradiol replacement therapy. Rats were divided into 6 groups: 1) Sham control group; 2) OVX + d-gal 100 mg/kg group (OVX + d-gal); 3–5) OVX, d-gal and Res 20, 40, 80 mg/kg treated groups; and 6) OVX, d-gal and estradiol valerate 0.8 mg/kg treated group (ET). Twelve weeks later, in a Morris water maze test, the OVX + d-gal rats exhibited a significant memory impairment compared with the Sham control rats, which was accompanied by decreased total superoxide dismutase (T-SOD) and glutathione peroxidase (GSH-Px) activities and an increased thiobarbituric acid reactive substances (TBARS) level in the serum. In addition, the TBARS and protein carbonylation levels increased in the hippocampus. The beneficial roles of the 40 and 80 mg/kg Res treatments were manifested in the prevention of memory decline and markedly decreased oxidant stress indices. The disruption of the cristae in the mitochondria and the irregular nuclei and condensed chromatin in the pyramidal cells of the hippocampal CA1 region were also reduced after Res treatment. Furthermore, edema in the endometrium and lymphocyte infiltration was avoided in all three of the Res-treated groups compared with the ET group. These results suggest that Res is useful not only in protecting OVX + d-gal rats from developing memory decline by increasing the anti-oxidation but also in avoiding the effects on the uterus." @default.
• W1970642677 created "2016-06-24" @default.
• W1970642677 creator A5002540257 @default.
• W1970642677 creator A5010276529 @default.
• W1970642677 creator A5012193053 @default.
• W1970642677 creator A5026222977 @default.
• W1970642677 creator A5031099164 @default.
• W1970642677 creator A5039062226 @default.
• W1970642677 creator A5067304111 @default.
• W1970642677 creator A5069178173 @default.
• W1970642677 creator A5078984452 @default.
• W1970642677 creator A5079576759 @default.
• W1970642677 creator A5080817250 @default.
• W1970642677 date "2012-07-01" @default.
• W1970642677 modified "2023-09-23" @default.
• W1970642677 title "Long-term resveratrol consumption protects ovariectomized rats chronically treated with d-galactose from developing memory decline without effects on the uterus" @default.
• W1970642677 cites W123657597 @default.
• W1970642677 cites W1495220312 @default.
• W1970642677 cites W1532774114 @default.
• W1970642677 cites W1537739899 @default.
• W1970642677 cites W1921640813 @default.
• W1970642677 cites W1964910828 @default.
• W1970642677 cites W1977433941 @default.
• W1970642677 cites W1978840911 @default.
• W1970642677 cites W1980327119 @default.
• W1970642677 cites W1983151735 @default.
• W1970642677 cites W1985591678 @default.
• W1970642677 cites W1986400646 @default.
• W1970642677 cites W1989954799 @default.
• W1970642677 cites W1993637512 @default.
• W1970642677 cites W1995100225 @default.
• W1970642677 cites W1996583548 @default.
• W1970642677 cites W1997849655 @default.
• W1970642677 cites W1998269359 @default.
• W1970642677 cites W2002686380 @default.
• W1970642677 cites W2003041544 @default.
• W1970642677 cites W2013924694 @default.
• W1970642677 cites W2014323395 @default.
• W1970642677 cites W2014941190 @default.
• W1970642677 cites W2016770736 @default.
• W1970642677 cites W2018384424 @default.
• W1970642677 cites W2023831571 @default.
• W1970642677 cites W2025714632 @default.
• W1970642677 cites W2025836762 @default.
• W1970642677 cites W2027487760 @default.
• W1970642677 cites W2029364884 @default.
• W1970642677 cites W2032697919 @default.
• W1970642677 cites W2034152593 @default.
• W1970642677 cites W2036928362 @default.
• W1970642677 cites W2038003980 @default.
• W1970642677 cites W2040365242 @default.
• W1970642677 cites W2045033455 @default.
• W1970642677 cites W2053995027 @default.
• W1970642677 cites W2057895866 @default.
• W1970642677 cites W2059382716 @default.
• W1970642677 cites W2059426523 @default.
• W1970642677 cites W2061029688 @default.
• W1970642677 cites W2064896025 @default.
• W1970642677 cites W2066633730 @default.
• W1970642677 cites W2075001365 @default.
• W1970642677 cites W2080683779 @default.
• W1970642677 cites W2081848351 @default.
• W1970642677 cites W2083383033 @default.
• W1970642677 cites W2084550095 @default.
• W1970642677 cites W2086149931 @default.
• W1970642677 cites W2089982008 @default.
• W1970642677 cites W2100592280 @default.
• W1970642677 cites W2101861123 @default.
• W1970642677 cites W2106443532 @default.
• W1970642677 cites W2106920456 @default.
• W1970642677 cites W2109852271 @default.
• W1970642677 cites W2111480326 @default.
• W1970642677 cites W2118497091 @default.
• W1970642677 cites W2119351189 @default.
• W1970642677 cites W2126619846 @default.
• W1970642677 cites W2131722081 @default.
• W1970642677 cites W2132673369 @default.
• W1970642677 cites W2141358477 @default.
• W1970642677 cites W2156909849 @default.
• W1970642677 cites W2161585328 @default.
• W1970642677 cites W2167703944 @default.
• W1970642677 cites W2168024298 @default.
• W1970642677 cites W2169473035 @default.
• W1970642677 cites W2172273404 @default.
• W1970642677 cites W4211079490 @default.
• W1970642677 cites W4244188348 @default.
• W1970642677 doi "https://doi.org/10.1016/j.brainres.2012.05.040" @default.
• W1970642677 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22647751" @default.
• W1970642677 hasPublicationYear "2012" @default.
• W1970642677 type Work @default.
• W1970642677 sameAs 1970642677 @default.
• W1970642677 citedByCount "40" @default.
• W1970642677 countsByYear W19706426772013 @default.
• W1970642677 countsByYear W19706426772014 @default.
• W1970642677 countsByYear W19706426772015 @default.
• W1970642677 countsByYear W19706426772016 @default.
• W1970642677 countsByYear W19706426772017 @default.
• W1970642677 countsByYear W19706426772018 @default.

• next