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- W1970653756 abstract "Human rhinovirus (HRV) 3C protease was inactivated by a series of S-nitrosothiols. These compounds exhibited different inhibitory activities in a time- and concentration-dependent manner with second-order rate constants (kinact/K(I)) ranging from 131 to 5360 M(-1) min(-1). The inactive enzyme could be re-activated by DTT, GSH and ascorbate, which indicated the inactivation mechanism was through an S-transnitrosylation process." @default.
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- W1970653756 date "2000-09-01" @default.
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- W1970653756 title "S-Nitrosothiols as novel, reversible inhibitors of human rhinovirus 3C protease" @default.
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- W1970653756 doi "https://doi.org/10.1016/s0960-894x(00)00420-0" @default.
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