Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970684712> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1970684712 endingPage "676" @default.
- W1970684712 startingPage "669" @default.
- W1970684712 abstract "The urinary excretion and proximal tubular reabsorption of beta-2-microglobulin was studied in 17 healthy newborn infants in relation to gestational and post-natal age. The effect of IRDS and non-conjugated hyperbilirubinemia on the tubular reabsorption of the protein was evaluated in 10 IRDS infants and 14 infants with non-conjugated hyperbilirubinemia. The urinary excretion of beta-2-microglobulin was determined under standardized conditions. When GFR was determined, the single injection clearance method was used. The filtered load of beta-2-microglobulin was found to increase with increasing gestational age. This was due to a rise in plasma beta-2-microglobulin concentration as well as to a rise in the GFR. Although the smallest filtered load was recorded in infants with a mean GA of 32.4 weeks, these infants had a lower fractional reabsorption of the protein (88%) than infants with a mean GA of 35.0 weeks or more (98%). In infants with a GA of 35 weeks or more a glomerulo-tubular balance for beta-2-microglobulin apparently was established. In these infants the filtered load of beta-2-microglobulin increased rapidly during the first days of life. This was paralleled by an increase in the reabsorptive capacity for the protein. In infants with IRDS and in infants with non-conjugated hyperbilirubinemia the fractional reabsorption of beta-2-microglobulin was lower than in control infants of a corresponding gestational and postnatal age. This indicates, that in the neonatal period, the proximal tubular transporting capacity is more vulnerable than the glomerular filtration rate in states of hypoxia and hyperbilirubinemia." @default.
- W1970684712 created "2016-06-24" @default.
- W1970684712 creator A5034295204 @default.
- W1970684712 creator A5050655291 @default.
- W1970684712 date "1979-09-01" @default.
- W1970684712 modified "2023-10-03" @default.
- W1970684712 title "BETA-2-MICROGLOBULIN, AN INDICATOR OF RENAL TUBULAR MATURATION AND DYSFUNCTION IN THE NEWBORN" @default.
- W1970684712 cites W1964471328 @default.
- W1970684712 cites W2009020576 @default.
- W1970684712 cites W2013761711 @default.
- W1970684712 cites W2017090582 @default.
- W1970684712 cites W2017187927 @default.
- W1970684712 cites W2021447329 @default.
- W1970684712 cites W2024751482 @default.
- W1970684712 cites W2026936244 @default.
- W1970684712 cites W2050349572 @default.
- W1970684712 cites W2054273616 @default.
- W1970684712 cites W2066239597 @default.
- W1970684712 cites W2071048569 @default.
- W1970684712 cites W2088107759 @default.
- W1970684712 cites W2090053659 @default.
- W1970684712 cites W2094066576 @default.
- W1970684712 cites W2094244434 @default.
- W1970684712 cites W2122598042 @default.
- W1970684712 cites W2178090130 @default.
- W1970684712 cites W4247759328 @default.
- W1970684712 doi "https://doi.org/10.1111/j.1651-2227.1979.tb18436.x" @default.
- W1970684712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/93393" @default.
- W1970684712 hasPublicationYear "1979" @default.
- W1970684712 type Work @default.
- W1970684712 sameAs 1970684712 @default.
- W1970684712 citedByCount "37" @default.
- W1970684712 countsByYear W19706847122018 @default.
- W1970684712 countsByYear W19706847122019 @default.
- W1970684712 crossrefType "journal-article" @default.
- W1970684712 hasAuthorship W1970684712A5034295204 @default.
- W1970684712 hasAuthorship W1970684712A5050655291 @default.
- W1970684712 hasConcept C10146269 @default.
- W1970684712 hasConcept C126322002 @default.
- W1970684712 hasConcept C134018914 @default.
- W1970684712 hasConcept C159641895 @default.
- W1970684712 hasConcept C161457703 @default.
- W1970684712 hasConcept C199360897 @default.
- W1970684712 hasConcept C21957315 @default.
- W1970684712 hasConcept C2776174256 @default.
- W1970684712 hasConcept C2778376644 @default.
- W1970684712 hasConcept C2779234561 @default.
- W1970684712 hasConcept C2780091579 @default.
- W1970684712 hasConcept C41008148 @default.
- W1970684712 hasConcept C54355233 @default.
- W1970684712 hasConcept C56906281 @default.
- W1970684712 hasConcept C71924100 @default.
- W1970684712 hasConcept C77411442 @default.
- W1970684712 hasConcept C86803240 @default.
- W1970684712 hasConceptScore W1970684712C10146269 @default.
- W1970684712 hasConceptScore W1970684712C126322002 @default.
- W1970684712 hasConceptScore W1970684712C134018914 @default.
- W1970684712 hasConceptScore W1970684712C159641895 @default.
- W1970684712 hasConceptScore W1970684712C161457703 @default.
- W1970684712 hasConceptScore W1970684712C199360897 @default.
- W1970684712 hasConceptScore W1970684712C21957315 @default.
- W1970684712 hasConceptScore W1970684712C2776174256 @default.
- W1970684712 hasConceptScore W1970684712C2778376644 @default.
- W1970684712 hasConceptScore W1970684712C2779234561 @default.
- W1970684712 hasConceptScore W1970684712C2780091579 @default.
- W1970684712 hasConceptScore W1970684712C41008148 @default.
- W1970684712 hasConceptScore W1970684712C54355233 @default.
- W1970684712 hasConceptScore W1970684712C56906281 @default.
- W1970684712 hasConceptScore W1970684712C71924100 @default.
- W1970684712 hasConceptScore W1970684712C77411442 @default.
- W1970684712 hasConceptScore W1970684712C86803240 @default.
- W1970684712 hasIssue "5" @default.
- W1970684712 hasLocation W19706847121 @default.
- W1970684712 hasLocation W19706847122 @default.
- W1970684712 hasOpenAccess W1970684712 @default.
- W1970684712 hasPrimaryLocation W19706847121 @default.
- W1970684712 hasRelatedWork W1524613404 @default.
- W1970684712 hasRelatedWork W1856891355 @default.
- W1970684712 hasRelatedWork W1974831299 @default.
- W1970684712 hasRelatedWork W1998090409 @default.
- W1970684712 hasRelatedWork W2017052050 @default.
- W1970684712 hasRelatedWork W2065485959 @default.
- W1970684712 hasRelatedWork W2092933224 @default.
- W1970684712 hasRelatedWork W2093016732 @default.
- W1970684712 hasRelatedWork W2316915683 @default.
- W1970684712 hasRelatedWork W2408857555 @default.
- W1970684712 hasVolume "68" @default.
- W1970684712 isParatext "false" @default.
- W1970684712 isRetracted "false" @default.
- W1970684712 magId "1970684712" @default.
- W1970684712 workType "article" @default.