FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970691750> ?p ?o ?g. }

• W1970691750 abstract "Members of the 14-3-3 protein family have been identified as regulatory molecules in intracellular signaling pathways and cell cycle control. Previously, the first Echinococcus 14-3-3 isoform (E14-3-3.1) was isolated from E. granulosus and E. multilocularis metacestode stages. Hyperexpression of this isoform was claimed to be associated with non-restricted tumor-like growth of the E. multilocularis metacestode. In this report, we describe the characterization of a 14-3-3 cDNA from E. granulosus and E. multilocularis corresponding to a second isoform of this family, E14-3-3.2. The characterized 14-3-3 gene was interrupted by two introns whose sequence and positions were conserved in both Echinococcus species. The deduced amino acid sequence of E14-3-3.2 showed 88% identity to the E14-3-3.1 isoform and 52% identity to a third Echinococcus isoform (E14-3-3.3) described by other authors. These findings, coupled to Southern blot analysis, suggest the presence of more than one 14-3-3 gene in Echinococcus. Phylogenenetically, the Echinococcus 14-3-3.1 and 14-3-3.2 isoforms appeared to cluster with zeta-type (pro-tumorigenic) 14-3-3 isoforms from closely related organisms, whereas the E14-3-3.3 isoform grouped with 14-3-3 epsilon isoforms. The presence of more than one 14-3-3 isoform might indicate isoform-specific roles in the different parasite stages of Echinococcus." @default.
• W1970691750 created "2016-06-24" @default.
• W1970691750 creator A5009904850 @default.
• W1970691750 creator A5028602536 @default.
• W1970691750 creator A5053218696 @default.
• W1970691750 creator A5081980640 @default.
• W1970691750 creator A5091505435 @default.
• W1970691750 date "2004-06-25" @default.
• W1970691750 modified "2023-10-01" @default.
• W1970691750 title "14-3-3 gene characterization and description of a second 14-3-3 isoform in both Echinococcus granulosus and E. multilocularis" @default.
• W1970691750 cites W1518742657 @default.
• W1970691750 cites W1549282212 @default.
• W1970691750 cites W1569287373 @default.
• W1970691750 cites W1965303089 @default.
• W1970691750 cites W1972008234 @default.
• W1970691750 cites W1988072445 @default.
• W1970691750 cites W1996386189 @default.
• W1970691750 cites W1998147157 @default.
• W1970691750 cites W2002370642 @default.
• W1970691750 cites W2002994564 @default.
• W1970691750 cites W2011924375 @default.
• W1970691750 cites W2014161029 @default.
• W1970691750 cites W2026600923 @default.
• W1970691750 cites W2039223690 @default.
• W1970691750 cites W2060517342 @default.
• W1970691750 cites W2071957945 @default.
• W1970691750 cites W2079280938 @default.
• W1970691750 cites W2085462220 @default.
• W1970691750 cites W2097382368 @default.
• W1970691750 cites W2103513327 @default.
• W1970691750 cites W2134170465 @default.
• W1970691750 cites W2138270253 @default.
• W1970691750 cites W2141305132 @default.
• W1970691750 cites W2156434383 @default.
• W1970691750 doi "https://doi.org/10.1007/s00436-004-1147-z" @default.
• W1970691750 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15221462" @default.
• W1970691750 hasPublicationYear "2004" @default.
• W1970691750 type Work @default.
• W1970691750 sameAs 1970691750 @default.
• W1970691750 citedByCount "10" @default.
• W1970691750 countsByYear W19706917502014 @default.
• W1970691750 countsByYear W19706917502016 @default.
• W1970691750 countsByYear W19706917502020 @default.
• W1970691750 crossrefType "journal-article" @default.
• W1970691750 hasAuthorship W1970691750A5009904850 @default.
• W1970691750 hasAuthorship W1970691750A5028602536 @default.
• W1970691750 hasAuthorship W1970691750A5053218696 @default.
• W1970691750 hasAuthorship W1970691750A5081980640 @default.
• W1970691750 hasAuthorship W1970691750A5091505435 @default.
• W1970691750 hasBestOaLocation W19706917502 @default.
• W1970691750 hasConcept C104317684 @default.
• W1970691750 hasConcept C153911025 @default.
• W1970691750 hasConcept C165901193 @default.
• W1970691750 hasConcept C167625842 @default.
• W1970691750 hasConcept C187882448 @default.
• W1970691750 hasConcept C203014093 @default.
• W1970691750 hasConcept C2777028278 @default.
• W1970691750 hasConcept C2779452502 @default.
• W1970691750 hasConcept C2779482186 @default.
• W1970691750 hasConcept C2779687537 @default.
• W1970691750 hasConcept C2779752401 @default.
• W1970691750 hasConcept C2780340127 @default.
• W1970691750 hasConcept C53345823 @default.
• W1970691750 hasConcept C54355233 @default.
• W1970691750 hasConcept C86803240 @default.
• W1970691750 hasConcept C90856448 @default.
• W1970691750 hasConceptScore W1970691750C104317684 @default.
• W1970691750 hasConceptScore W1970691750C153911025 @default.
• W1970691750 hasConceptScore W1970691750C165901193 @default.
• W1970691750 hasConceptScore W1970691750C167625842 @default.
• W1970691750 hasConceptScore W1970691750C187882448 @default.
• W1970691750 hasConceptScore W1970691750C203014093 @default.
• W1970691750 hasConceptScore W1970691750C2777028278 @default.
• W1970691750 hasConceptScore W1970691750C2779452502 @default.
• W1970691750 hasConceptScore W1970691750C2779482186 @default.
• W1970691750 hasConceptScore W1970691750C2779687537 @default.
• W1970691750 hasConceptScore W1970691750C2779752401 @default.
• W1970691750 hasConceptScore W1970691750C2780340127 @default.
• W1970691750 hasConceptScore W1970691750C53345823 @default.
• W1970691750 hasConceptScore W1970691750C54355233 @default.
• W1970691750 hasConceptScore W1970691750C86803240 @default.
• W1970691750 hasConceptScore W1970691750C90856448 @default.
• W1970691750 hasIssue "5" @default.
• W1970691750 hasLocation W19706917501 @default.
• W1970691750 hasLocation W19706917502 @default.
• W1970691750 hasLocation W19706917503 @default.
• W1970691750 hasOpenAccess W1970691750 @default.
• W1970691750 hasPrimaryLocation W19706917501 @default.
• W1970691750 hasRelatedWork W1586554954 @default.
• W1970691750 hasRelatedWork W1970691750 @default.
• W1970691750 hasRelatedWork W1992137363 @default.
• W1970691750 hasRelatedWork W2082291715 @default.
• W1970691750 hasRelatedWork W2090750390 @default.
• W1970691750 hasRelatedWork W2103440335 @default.
• W1970691750 hasRelatedWork W2129719828 @default.
• W1970691750 hasRelatedWork W2779256195 @default.
• W1970691750 hasRelatedWork W2917110130 @default.
• W1970691750 hasRelatedWork W2983719767 @default.
• W1970691750 hasVolume "93" @default.
• W1970691750 isParatext "false" @default.

• next