Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970706367> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W1970706367 endingPage "168" @default.
- W1970706367 startingPage "162" @default.
- W1970706367 abstract "A progressive pulmonary disease resulting in severe respiratory failure and death in an average of 3 weeks was diagnosed in 11 young Dalmatian dogs. The dogs were from 4 litters, all genetically related by a common ancestor. The initial clinical signs were tachypnea and noisy respiration. Respiratory distress developed shortly before death and was characterized by strenuous and rapid respirations, along with cyanosis and vomiting. On blood gas analysis, there were severe arterial hypoxemia, hypercapma, and marked alveolar‐arterial oxygen difference. Radiographically, a diffuse pattern of alveolar, interstitial, and peribronchial densities was observed in the lungs. Most dogs developed pneumomediastinum and gastroesophageal intussusception in the terminal phase of the disease. There was no response to treatment with antibiotics, corticosteroids, diuretics, or oxygen. At necropsy, the lungs were wet, heavy, and relatively airless. Absence of 1 kidney in 2 dogs and severe internal hydrocephalus in 2 dogs were additional necropsy findings. Pulmonary histopathology included metaplasia and atypia of the alveolar and bronchiolar epithelium, a nonpurulent inflammatory reaction characterized mainly by mononuclear cells and macrophages, eosinophilic hyaline membrane formation, and focal pulmonary fibrosis. The histological manifestations were typical of acute lung injury. Clinically, the findings were consistent with adult respiratory distress syndrome (ARDS), except for the relatively long course. No known risk factors for ARDS, such as trauma, toxin exposure, infection, or endotoxemia could be identified. The relationship of the other abnormalities (ie, renal aplasia, hydrocephalus) to the pulmonary disease also remains obscure. An inherited defect is suspected, because segregation analysis of the 4 litters suggests autosomal recessive inheritance." @default.
- W1970706367 created "2016-06-24" @default.
- W1970706367 creator A5009530516 @default.
- W1970706367 creator A5051822983 @default.
- W1970706367 creator A5077589465 @default.
- W1970706367 creator A5081175105 @default.
- W1970706367 creator A5083331620 @default.
- W1970706367 creator A5083416463 @default.
- W1970706367 date "1995-05-01" @default.
- W1970706367 modified "2023-09-30" @default.
- W1970706367 title "Lung Injury Leading to Respiratory Distress Syndrome in Young Dalmatian Dogs" @default.
- W1970706367 cites W1977967607 @default.
- W1970706367 cites W1978354645 @default.
- W1970706367 cites W1997479618 @default.
- W1970706367 cites W2021681536 @default.
- W1970706367 cites W2026521622 @default.
- W1970706367 cites W2044126015 @default.
- W1970706367 cites W2054433983 @default.
- W1970706367 cites W2066305448 @default.
- W1970706367 doi "https://doi.org/10.1111/j.1939-1676.1995.tb03290.x" @default.
- W1970706367 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7674217" @default.
- W1970706367 hasPublicationYear "1995" @default.
- W1970706367 type Work @default.
- W1970706367 sameAs 1970706367 @default.
- W1970706367 citedByCount "17" @default.
- W1970706367 countsByYear W19707063672012 @default.
- W1970706367 countsByYear W19707063672014 @default.
- W1970706367 countsByYear W19707063672015 @default.
- W1970706367 countsByYear W19707063672017 @default.
- W1970706367 countsByYear W19707063672018 @default.
- W1970706367 countsByYear W19707063672019 @default.
- W1970706367 crossrefType "journal-article" @default.
- W1970706367 hasAuthorship W1970706367A5009530516 @default.
- W1970706367 hasAuthorship W1970706367A5051822983 @default.
- W1970706367 hasAuthorship W1970706367A5077589465 @default.
- W1970706367 hasAuthorship W1970706367A5081175105 @default.
- W1970706367 hasAuthorship W1970706367A5083331620 @default.
- W1970706367 hasAuthorship W1970706367A5083416463 @default.
- W1970706367 hasConcept C126322002 @default.
- W1970706367 hasConcept C141983124 @default.
- W1970706367 hasConcept C142724271 @default.
- W1970706367 hasConcept C2776348555 @default.
- W1970706367 hasConcept C2776779939 @default.
- W1970706367 hasConcept C2776888751 @default.
- W1970706367 hasConcept C2777050789 @default.
- W1970706367 hasConcept C2777714996 @default.
- W1970706367 hasConcept C2778312941 @default.
- W1970706367 hasConcept C2780283014 @default.
- W1970706367 hasConcept C2909621147 @default.
- W1970706367 hasConcept C42219234 @default.
- W1970706367 hasConcept C71924100 @default.
- W1970706367 hasConcept C9418649 @default.
- W1970706367 hasConceptScore W1970706367C126322002 @default.
- W1970706367 hasConceptScore W1970706367C141983124 @default.
- W1970706367 hasConceptScore W1970706367C142724271 @default.
- W1970706367 hasConceptScore W1970706367C2776348555 @default.
- W1970706367 hasConceptScore W1970706367C2776779939 @default.
- W1970706367 hasConceptScore W1970706367C2776888751 @default.
- W1970706367 hasConceptScore W1970706367C2777050789 @default.
- W1970706367 hasConceptScore W1970706367C2777714996 @default.
- W1970706367 hasConceptScore W1970706367C2778312941 @default.
- W1970706367 hasConceptScore W1970706367C2780283014 @default.
- W1970706367 hasConceptScore W1970706367C2909621147 @default.
- W1970706367 hasConceptScore W1970706367C42219234 @default.
- W1970706367 hasConceptScore W1970706367C71924100 @default.
- W1970706367 hasConceptScore W1970706367C9418649 @default.
- W1970706367 hasIssue "3" @default.
- W1970706367 hasLocation W19707063671 @default.
- W1970706367 hasLocation W19707063672 @default.
- W1970706367 hasOpenAccess W1970706367 @default.
- W1970706367 hasPrimaryLocation W19707063671 @default.
- W1970706367 hasRelatedWork W1631951333 @default.
- W1970706367 hasRelatedWork W2109479381 @default.
- W1970706367 hasRelatedWork W2152965418 @default.
- W1970706367 hasRelatedWork W2327441460 @default.
- W1970706367 hasRelatedWork W2339726819 @default.
- W1970706367 hasRelatedWork W2395742511 @default.
- W1970706367 hasRelatedWork W2599261489 @default.
- W1970706367 hasRelatedWork W2601736018 @default.
- W1970706367 hasRelatedWork W2894219486 @default.
- W1970706367 hasRelatedWork W3125587469 @default.
- W1970706367 hasVolume "9" @default.
- W1970706367 isParatext "false" @default.
- W1970706367 isRetracted "false" @default.
- W1970706367 magId "1970706367" @default.
- W1970706367 workType "article" @default.