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- W1970748081 abstract "Summary We investigated the frequencies of early populations of progenitors in aplastic anaemia (AA) bone marrow, from patients with a range of disease severity, compared with normal. Double-colour immunofluorescent staining for CD34 and CD33 was carried out on bone marrow mononuclear cells (BMMC) and analysed using fluorescence activated cell sorting (FACS), AA CD34+ cells were reduced by 68% compared to normal. In addition, AA CD33+ cells and the three progenitor subsets (CD34+/CD33–, CD34+/CD33+ and CD34–/CD33+) were reduced by 44–80%. Our data lend further support for an early stem cell deficiency in AA." @default.
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- W1970748081 date "1994-02-01" @default.
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- W1970748081 title "Haemopoietic progenitor cells are reduced in aplastic anaemia" @default.
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- W1970748081 doi "https://doi.org/10.1111/j.1365-2141.1994.tb04761.x" @default.
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