Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970763846> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W1970763846 abstract "Dendritic cells (DCs) are the most potent antigen presenting cells, which can stimulate a cellular immune response against malignant tumor cells. Many authors have described the phenomenon of tumor infiltration by dendritic cells and emphasized an immunosuppressive tumor influence on DC function. In the present study, we examined the presence of myeloid CD1c+ (BDCA-1+) dendritic cells and lymphoid/plasmacytoid CD303+ (BDCA-2+) dendritic cells in peripheral blood, lymph nodes and cancer tissue of patients with non-small cell lung cancer (NSCLC). Fifty male patients treated surgically for NSCLC stages I-IIIa without neoadjuvant chemotherapy were included. Employing a multiparameter flow cytometry for CD1c, CD19, CD123 and CD303, we observed an accumulation of immature DCs in the tissues involved in the neoplasmatic process with the predominance of lymphoid/plasmacytoid over myeloid DCs. Moreover, in peripheral blood NSCLC patients had a significantly lower percentage of CD1c+ DCs than healthy donors. Our results suggest that NSCLC cells might hamper the maturation of DCs, thus escaping an efficient immune response." @default.
- W1970763846 created "2016-06-24" @default.
- W1970763846 creator A5046643498 @default.
- W1970763846 creator A5048934421 @default.
- W1970763846 creator A5067664293 @default.
- W1970763846 creator A5085299270 @default.
- W1970763846 date "2008-01-01" @default.
- W1970763846 modified "2023-10-01" @default.
- W1970763846 title "CD1c+ and CD303+ dendritic cells in peripheral blood, lymph nodes and tumor tissue of patients with non-small cell lung cancer" @default.
- W1970763846 doi "https://doi.org/10.3892/or.19.1.237" @default.
- W1970763846 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18097601" @default.
- W1970763846 hasPublicationYear "2008" @default.
- W1970763846 type Work @default.
- W1970763846 sameAs 1970763846 @default.
- W1970763846 citedByCount "20" @default.
- W1970763846 countsByYear W19707638462015 @default.
- W1970763846 countsByYear W19707638462016 @default.
- W1970763846 countsByYear W19707638462017 @default.
- W1970763846 countsByYear W19707638462019 @default.
- W1970763846 countsByYear W19707638462020 @default.
- W1970763846 countsByYear W19707638462021 @default.
- W1970763846 countsByYear W19707638462022 @default.
- W1970763846 countsByYear W19707638462023 @default.
- W1970763846 crossrefType "journal-article" @default.
- W1970763846 hasAuthorship W1970763846A5046643498 @default.
- W1970763846 hasAuthorship W1970763846A5048934421 @default.
- W1970763846 hasAuthorship W1970763846A5067664293 @default.
- W1970763846 hasAuthorship W1970763846A5085299270 @default.
- W1970763846 hasBestOaLocation W19707638461 @default.
- W1970763846 hasConcept C121608353 @default.
- W1970763846 hasConcept C126322002 @default.
- W1970763846 hasConcept C142724271 @default.
- W1970763846 hasConcept C147483822 @default.
- W1970763846 hasConcept C203014093 @default.
- W1970763846 hasConcept C2776090121 @default.
- W1970763846 hasConcept C2778170410 @default.
- W1970763846 hasConcept C2779282312 @default.
- W1970763846 hasConcept C3753494 @default.
- W1970763846 hasConcept C502942594 @default.
- W1970763846 hasConcept C553184892 @default.
- W1970763846 hasConcept C67662055 @default.
- W1970763846 hasConcept C71924100 @default.
- W1970763846 hasConcept C86803240 @default.
- W1970763846 hasConcept C8891405 @default.
- W1970763846 hasConceptScore W1970763846C121608353 @default.
- W1970763846 hasConceptScore W1970763846C126322002 @default.
- W1970763846 hasConceptScore W1970763846C142724271 @default.
- W1970763846 hasConceptScore W1970763846C147483822 @default.
- W1970763846 hasConceptScore W1970763846C203014093 @default.
- W1970763846 hasConceptScore W1970763846C2776090121 @default.
- W1970763846 hasConceptScore W1970763846C2778170410 @default.
- W1970763846 hasConceptScore W1970763846C2779282312 @default.
- W1970763846 hasConceptScore W1970763846C3753494 @default.
- W1970763846 hasConceptScore W1970763846C502942594 @default.
- W1970763846 hasConceptScore W1970763846C553184892 @default.
- W1970763846 hasConceptScore W1970763846C67662055 @default.
- W1970763846 hasConceptScore W1970763846C71924100 @default.
- W1970763846 hasConceptScore W1970763846C86803240 @default.
- W1970763846 hasConceptScore W1970763846C8891405 @default.
- W1970763846 hasLocation W19707638461 @default.
- W1970763846 hasLocation W19707638462 @default.
- W1970763846 hasOpenAccess W1970763846 @default.
- W1970763846 hasPrimaryLocation W19707638461 @default.
- W1970763846 hasRelatedWork W129094102 @default.
- W1970763846 hasRelatedWork W1972481641 @default.
- W1970763846 hasRelatedWork W2028713402 @default.
- W1970763846 hasRelatedWork W2060454132 @default.
- W1970763846 hasRelatedWork W2083909888 @default.
- W1970763846 hasRelatedWork W2220102944 @default.
- W1970763846 hasRelatedWork W2356500445 @default.
- W1970763846 hasRelatedWork W2375999619 @default.
- W1970763846 hasRelatedWork W2947662066 @default.
- W1970763846 hasRelatedWork W3097688833 @default.
- W1970763846 isParatext "false" @default.
- W1970763846 isRetracted "false" @default.
- W1970763846 magId "1970763846" @default.
- W1970763846 workType "article" @default.