FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970780140> ?p ?o ?g. }

• W1970780140 endingPage "6730" @default.
• W1970780140 startingPage "6726" @default.
• W1970780140 abstract "Life falls into three fundamental domains--Archaea, Bacteria, and Eucarya (formerly archaebacteria, eubacteria, and eukaryotes,. respectively). Though Archaea lack nuclei and share many morphological features with Bacteria, molecular analyses, principally of the transcription and translation machineries, have suggested that Archaea are more related to Eucarya than to Bacteria. Currently, little is known about the archaeal cell division apparatus. In Bacteria, a crucial component of the cell division machinery is FtsZ, a GTPase that localizes to a ring at the site of septation. Interestingly, FtsZ is distantly related in sequence to eukaryotic tubulins, which also interact with GTP and are components of the eukaryotic cell cytoskeleton. By screening for the ability to bind radiolabeled nucleotides, we have identified a protein of the hyperthermophilic archaeon Pyrococcus woesei that interacts tightly and specifically with GTP. Furthermore, through screening an expression library of P. woesei genomic DNA, we have cloned the gene encoding this protein. Sequence comparisons reveal that the P. woesei GTP-binding protein is strikingly related in sequence to eubacterial FtsZ and is marginally more similar to eukaryotic tubulins than are bacterial FtsZ proteins. Phylogenetic analyses reinforce the notion that there is an evolutionary linkage between FtsZ and tubulins. These findings suggest that the archaeal cell division apparatus may be fundamentally similar to that of Bacteria and lead us to consider the evolutionary relationships between Archaea, Bacteria, and Eucarya." @default.
• W1970780140 created "2016-06-24" @default.
• W1970780140 creator A5035901668 @default.
• W1970780140 creator A5061795154 @default.
• W1970780140 date "1996-06-25" @default.
• W1970780140 modified "2023-09-27" @default.
• W1970780140 title "An archaebacterial homologue of the essential eubacterial cell division protein FtsZ." @default.
• W1970780140 cites W1020194079 @default.
• W1970780140 cites W1630044161 @default.
• W1970780140 cites W1668246716 @default.
• W1970780140 cites W1946075442 @default.
• W1970780140 cites W1964038971 @default.
• W1970780140 cites W1964601681 @default.
• W1970780140 cites W1972909853 @default.
• W1970780140 cites W1977912508 @default.
• W1970780140 cites W1979098911 @default.
• W1970780140 cites W1987185394 @default.
• W1970780140 cites W1991207390 @default.
• W1970780140 cites W1991793263 @default.
• W1970780140 cites W1994991981 @default.
• W1970780140 cites W1995714662 @default.
• W1970780140 cites W2001469156 @default.
• W1970780140 cites W2002115528 @default.
• W1970780140 cites W2008133000 @default.
• W1970780140 cites W2009310436 @default.
• W1970780140 cites W2015292449 @default.
• W1970780140 cites W2021706188 @default.
• W1970780140 cites W2036567347 @default.
• W1970780140 cites W2045080033 @default.
• W1970780140 cites W2045684879 @default.
• W1970780140 cites W2049213972 @default.
• W1970780140 cites W2055380124 @default.
• W1970780140 cites W2061609869 @default.
• W1970780140 cites W2063291840 @default.
• W1970780140 cites W2076475173 @default.
• W1970780140 cites W2087463186 @default.
• W1970780140 cites W2095402208 @default.
• W1970780140 cites W2098386120 @default.
• W1970780140 cites W2106882534 @default.
• W1970780140 cites W2114000879 @default.
• W1970780140 cites W2114750851 @default.
• W1970780140 cites W2136692684 @default.
• W1970780140 cites W2166865790 @default.
• W1970780140 doi "https://doi.org/10.1073/pnas.93.13.6726" @default.
• W1970780140 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/39094" @default.
• W1970780140 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8692886" @default.
• W1970780140 hasPublicationYear "1996" @default.
• W1970780140 type Work @default.
• W1970780140 sameAs 1970780140 @default.
• W1970780140 citedByCount "64" @default.
• W1970780140 countsByYear W19707801402013 @default.
• W1970780140 countsByYear W19707801402014 @default.
• W1970780140 countsByYear W19707801402016 @default.
• W1970780140 countsByYear W19707801402017 @default.
• W1970780140 countsByYear W19707801402018 @default.
• W1970780140 countsByYear W19707801402020 @default.
• W1970780140 countsByYear W19707801402021 @default.
• W1970780140 countsByYear W19707801402023 @default.
• W1970780140 crossrefType "journal-article" @default.
• W1970780140 hasAuthorship W1970780140A5035901668 @default.
• W1970780140 hasAuthorship W1970780140A5061795154 @default.
• W1970780140 hasBestOaLocation W19707801402 @default.
• W1970780140 hasConcept C104317684 @default.
• W1970780140 hasConcept C118716 @default.
• W1970780140 hasConcept C1491633281 @default.
• W1970780140 hasConcept C167625842 @default.
• W1970780140 hasConcept C181199279 @default.
• W1970780140 hasConcept C199216141 @default.
• W1970780140 hasConcept C207332259 @default.
• W1970780140 hasConcept C2776237524 @default.
• W1970780140 hasConcept C523546767 @default.
• W1970780140 hasConcept C54355233 @default.
• W1970780140 hasConcept C550995028 @default.
• W1970780140 hasConcept C55493867 @default.
• W1970780140 hasConcept C85813293 @default.
• W1970780140 hasConcept C86803240 @default.
• W1970780140 hasConcept C95444343 @default.
• W1970780140 hasConceptScore W1970780140C104317684 @default.
• W1970780140 hasConceptScore W1970780140C118716 @default.
• W1970780140 hasConceptScore W1970780140C1491633281 @default.
• W1970780140 hasConceptScore W1970780140C167625842 @default.
• W1970780140 hasConceptScore W1970780140C181199279 @default.
• W1970780140 hasConceptScore W1970780140C199216141 @default.
• W1970780140 hasConceptScore W1970780140C207332259 @default.
• W1970780140 hasConceptScore W1970780140C2776237524 @default.
• W1970780140 hasConceptScore W1970780140C523546767 @default.
• W1970780140 hasConceptScore W1970780140C54355233 @default.
• W1970780140 hasConceptScore W1970780140C550995028 @default.
• W1970780140 hasConceptScore W1970780140C55493867 @default.
• W1970780140 hasConceptScore W1970780140C85813293 @default.
• W1970780140 hasConceptScore W1970780140C86803240 @default.
• W1970780140 hasConceptScore W1970780140C95444343 @default.
• W1970780140 hasIssue "13" @default.
• W1970780140 hasLocation W19707801401 @default.
• W1970780140 hasLocation W19707801402 @default.
• W1970780140 hasLocation W19707801403 @default.
• W1970780140 hasLocation W19707801404 @default.
• W1970780140 hasOpenAccess W1970780140 @default.

• next