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• W1970788068 abstract "A novel hybrid hydrogel was prepared and investigated based on silkworm silk fibroin and poly(<i >N</i>-isopropylacrylamide) (PNIPAAm). PNIPAAm was introduced to silk fibroin, the resultant composite hydrogel was examined, and freeze-dried SF/PNIPAAm scaffold was analyzed using LB-550 dynamic light scattering particle-size analyzer, circular dichroism (CD), and scanning electron microscopy (SEM). Our results suggested that the hybrid hydrogels owned the porous sponge-like structures, and the gelation time of SF/PNIPAAm hybrids decreased with an increase in temperature and concentration of each polymer. Results of rheological analysis suggested that the rheological property of resultant SF/PNIPAAm gel depended on the concentration combinations as well as the aging time, which elapsed after mixing the two polymers. Results of CD spectra demonstrated that pH showed little influence on the secondary structure of silk fibroin, and significant changes of <svg style=vertical-align:-0.20473pt;width:16.4375px; id=M1 height=17.9625 version=1.1 viewBox=0 0 16.4375 17.9625 width=16.4375 xmlns:xlink=http://www.w3.org/1999/xlink xmlns=http://www.w3.org/2000/svg> <g transform=matrix(.017,-0,0,-.017,.062,17.65)><path id=x47 d=M692 302v-28q-45 -6 -54.5 -17t-9.5 -55v-86q0 -62 7 -95q-7 -2 -32 -7.5l-37 -8l-35.5 -7.5t-40.5 -7t-38.5 -4t-40.5 -2q-165 0 -266 93t-101 243q0 84 32 151t86 108t121.5 63t142.5 22q29 0 62.5 -4t52 -7.5t47.5 -10.5t31 -7l15 -156l-28 -6q-17 87 -66.5 121.5&#xA;t-128.5 34.5q-117 0 -191 -80.5t-74 -216.5q0 -56 17 -110t49.5 -100.5t87.5 -74.5t124 -28q53 0 87 17q17 9 24.5 23t7.5 43v85q0 54 -15.5 67.5t-89.5 18.5v28h254z /></g> <g transform=matrix(.012,-0,0,-.012,12.213,9.488)><path id=x2032 d=M227 744l-123 -338l-31 15l73 368q12 3 41.5 -8t36.5 -20z /></g> </svg>, <svg style=vertical-align:-0.20473pt;width:19.975px; id=M2 height=17.9625 version=1.1 viewBox=0 0 19.975 17.9625 width=19.975 xmlns:xlink=http://www.w3.org/1999/xlink xmlns=http://www.w3.org/2000/svg> <g transform=matrix(.017,-0,0,-.017,.062,17.65)><use xlink:href=#x47/></g> <g transform=matrix(.012,-0,0,-.012,12.213,9.488)><use xlink:href=#x2032/></g><g transform=matrix(.012,-0,0,-.012,15.746,9.488)><use xlink:href=#x2032/></g> </svg>, and G&#x2a; as surrounding increase temperature above the lower critical solution temperature (LCST)." @default.
• W1970788068 created "2016-06-24" @default.
• W1970788068 creator A5043780745 @default.
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• W1970788068 date "2013-01-01" @default.
• W1970788068 modified "2023-09-27" @default.
• W1970788068 title "Preparation and Characterization of a Novel Hybrid Hydrogel Composed ofBombyx moriFibroin and Poly(N-isopropylacrylamide)" @default.
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• W1970788068 doi "https://doi.org/10.1155/2013/832710" @default.
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