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- W1970837652 abstract "In recent years the usefulness of the alpha 2 adrenoceptor agonist drugs has been recognized in equine practice. Several agents have become available and are now licensed for use in a number of countries. The principle actions of all alpha 2 adrenoceptor agonists are similar, in that they produce a reduction in heart rate and alteration of heart rhythm, an initial hypertension followed by a prolonged hypotension, a decrease in the cardiac output and respiratory depression. For clinical purposes, these agents produce sedation and analgesia, they are useful for premedication and markedly potentiate the effects of other sedative/analgesic agents. Differences in receptor specificity between the alpha 2 adrenoceptor agonists results in the distinguishing characteristics of the individual agents, particularly with respect to their duration of action, sedative effect and analgesic properties; their cardiopulmonary effects are however similar, when equipotent sedative doses are administered. When used in combination with other agents, the alpha 2 adrenoceptor agonists all appear to act in a similar manner, with the greatest difference being related to their duration of action." @default.
- W1970837652 created "2016-06-24" @default.
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- W1970837652 date "1996-11-01" @default.
- W1970837652 modified "2023-09-27" @default.
- W1970837652 title "Alpha2 adrenoceptor agonists in the horse—Areview" @default.
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- W1970837652 doi "https://doi.org/10.1016/s0007-1935(96)80118-7" @default.
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