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- W1970842012 abstract "The presence or absence of coronary artery disease was established by coronary angiography in 181 male patients (aged 40–60 years). The concentrations of cholesterol and triglycerides were determined in the sera of all patients. In addition, plasma lipoproteins were quantified by a recently developed quantitative lipoprotein electrophoresis based on densitometric scanning of lipoprotein bands visualized by polyanion precipitation after electrophoretic separation. The most pronounced differences between these two groups of patients were found in the concentrations of whole serum cholesterol, β-lipoprotein cholesterol and the β-lipoprotein/α-lipoprotein ratio. No marked differences were seen in the concentrations of serum triglycerides, pre-β-lipoprotein cholesterol or α-lipoprotein cholesterol. A combination of critical values for the concentrations of serum cholesterol and β-lipoprotein cholesterol and for the β-lipoprotein/α-lipoprotein ratio could be established. If exceeding at least two of the three critical values was used as the cut-off point between the two groups of patients, maximum differentiation of 50% could be achieved (81% correctly classified patients vs. 31% incorrectly classified). Introduction of the β-lipoprotein/α-lipoprotein ratio as criterion shifts the range of differentiation favorably, increasing it by about 10%. This effect cannot be achieved by regarding the level of α-lipoprotein cholesterol as criterion." @default.
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- W1970842012 date "1980-06-01" @default.
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- W1970842012 title "Serum lipoproteins and coronary artery disease (CAD) *1Comparison of the lipoprotein profile with the results of coronary angiography" @default.
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- W1970842012 doi "https://doi.org/10.1016/0021-9150(80)90235-x" @default.
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