FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970847994> ?p ?o ?g. }

• W1970847994 endingPage "824" @default.
• W1970847994 startingPage "820" @default.
• W1970847994 abstract "Abstract Interleukin‐23 (IL‐23), a novel cytokine composed of a newly identified p19 molecule and the p40 subunit of IL‐12, can stimulate the proliferation in vitro of memory T cells. We examined whether Colon 26 murine colon carcinoma cells that were retrovirally transduced with the p19 ‐linked p40 gene (Colon 26/IL‐23) could produce antitumor effects in inoculated mice. The growth of Colon 26/IL‐23 tumors developed in immunocompetent mice was significantly retarded and the tumors disappeared thereafter. Spleen cells from the mice that received Colon 26/IL‐23 cells produced significant amounts of interferon‐γ, when they were cultured with irradiated Colon 26 but not irrelevant cells. Depletion of CD8 + T cells suppressed the production of interferon‐γ. The mice that had rejected Colon 26/IL‐23 tumors were resistant to subsequent challenge of parent but not irrelevant tumor cells. Colon 26/IL‐23 tumors were not rejected in nude mice but the growth was retarded compared to parent tumors. Treatment of nude mice with anti‐asialo GM 1 antibody did not influence the growth of Colon 26/IL‐23 tumors. These data suggest that expression of IL‐23 in tumors produces T cell‐dependent antitumor effects and induces systemic immunity. © 2003 Wiley‐Liss, Inc." @default.
• W1970847994 created "2016-06-24" @default.
• W1970847994 creator A5012584390 @default.
• W1970847994 creator A5027582885 @default.
• W1970847994 creator A5027672648 @default.
• W1970847994 creator A5028781569 @default.
• W1970847994 creator A5036778299 @default.
• W1970847994 creator A5036824632 @default.
• W1970847994 creator A5052148013 @default.
• W1970847994 creator A5068601802 @default.
• W1970847994 creator A5082197799 @default.
• W1970847994 date "2003-05-15" @default.
• W1970847994 modified "2023-10-17" @default.
• W1970847994 title "Induction of systemic immunity by expression of interleukin-23 in murine colon carcinoma cells" @default.
• W1970847994 cites W1498865077 @default.
• W1970847994 cites W1509377507 @default.
• W1970847994 cites W1540648309 @default.
• W1970847994 cites W1556169045 @default.
• W1970847994 cites W1847326477 @default.
• W1970847994 cites W1964882815 @default.
• W1970847994 cites W1972464496 @default.
• W1970847994 cites W1991587280 @default.
• W1970847994 cites W2031501484 @default.
• W1970847994 cites W2074958393 @default.
• W1970847994 cites W2087905758 @default.
• W1970847994 cites W2088910535 @default.
• W1970847994 cites W2089182314 @default.
• W1970847994 cites W2098477883 @default.
• W1970847994 cites W2121895986 @default.
• W1970847994 cites W2133435354 @default.
• W1970847994 cites W2133922377 @default.
• W1970847994 cites W2144305464 @default.
• W1970847994 cites W2320525942 @default.
• W1970847994 cites W2325034463 @default.
• W1970847994 cites W4313333776 @default.
• W1970847994 doi "https://doi.org/10.1002/ijc.11160" @default.
• W1970847994 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12767068" @default.
• W1970847994 hasPublicationYear "2003" @default.
• W1970847994 type Work @default.
• W1970847994 sameAs 1970847994 @default.
• W1970847994 citedByCount "65" @default.
• W1970847994 countsByYear W19708479942012 @default.
• W1970847994 countsByYear W19708479942013 @default.
• W1970847994 countsByYear W19708479942014 @default.
• W1970847994 countsByYear W19708479942015 @default.
• W1970847994 countsByYear W19708479942019 @default.
• W1970847994 countsByYear W19708479942020 @default.
• W1970847994 countsByYear W19708479942021 @default.
• W1970847994 countsByYear W19708479942022 @default.
• W1970847994 crossrefType "journal-article" @default.
• W1970847994 hasAuthorship W1970847994A5012584390 @default.
• W1970847994 hasAuthorship W1970847994A5027582885 @default.
• W1970847994 hasAuthorship W1970847994A5027672648 @default.
• W1970847994 hasAuthorship W1970847994A5028781569 @default.
• W1970847994 hasAuthorship W1970847994A5036778299 @default.
• W1970847994 hasAuthorship W1970847994A5036824632 @default.
• W1970847994 hasAuthorship W1970847994A5052148013 @default.
• W1970847994 hasAuthorship W1970847994A5068601802 @default.
• W1970847994 hasAuthorship W1970847994A5082197799 @default.
• W1970847994 hasBestOaLocation W19708479941 @default.
• W1970847994 hasConcept C121608353 @default.
• W1970847994 hasConcept C126322002 @default.
• W1970847994 hasConcept C149532602 @default.
• W1970847994 hasConcept C154317977 @default.
• W1970847994 hasConcept C167672396 @default.
• W1970847994 hasConcept C202751555 @default.
• W1970847994 hasConcept C203014093 @default.
• W1970847994 hasConcept C2778690821 @default.
• W1970847994 hasConcept C2779341262 @default.
• W1970847994 hasConcept C2780931953 @default.
• W1970847994 hasConcept C2991914351 @default.
• W1970847994 hasConcept C3017875465 @default.
• W1970847994 hasConcept C502942594 @default.
• W1970847994 hasConcept C526805850 @default.
• W1970847994 hasConcept C55493867 @default.
• W1970847994 hasConcept C71924100 @default.
• W1970847994 hasConcept C86803240 @default.
• W1970847994 hasConcept C8891405 @default.
• W1970847994 hasConceptScore W1970847994C121608353 @default.
• W1970847994 hasConceptScore W1970847994C126322002 @default.
• W1970847994 hasConceptScore W1970847994C149532602 @default.
• W1970847994 hasConceptScore W1970847994C154317977 @default.
• W1970847994 hasConceptScore W1970847994C167672396 @default.
• W1970847994 hasConceptScore W1970847994C202751555 @default.
• W1970847994 hasConceptScore W1970847994C203014093 @default.
• W1970847994 hasConceptScore W1970847994C2778690821 @default.
• W1970847994 hasConceptScore W1970847994C2779341262 @default.
• W1970847994 hasConceptScore W1970847994C2780931953 @default.
• W1970847994 hasConceptScore W1970847994C2991914351 @default.
• W1970847994 hasConceptScore W1970847994C3017875465 @default.
• W1970847994 hasConceptScore W1970847994C502942594 @default.
• W1970847994 hasConceptScore W1970847994C526805850 @default.
• W1970847994 hasConceptScore W1970847994C55493867 @default.
• W1970847994 hasConceptScore W1970847994C71924100 @default.
• W1970847994 hasConceptScore W1970847994C86803240 @default.
• W1970847994 hasConceptScore W1970847994C8891405 @default.
• W1970847994 hasIssue "6" @default.
• W1970847994 hasLocation W19708479941 @default.

• next