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- W1970861895 abstract "LMWH (FraxiparineR), and NSAIDs (Aspirin, FeldeneR, IndocidR and ProfenidR) injected together in doses, 1mg/kg (Aspirin was used at 100 mg/kg), subcutaneously into rats 30 minutes before the thrombosis induction by LASER beams, increased the number of LASER beams required to induce platelet thrombus formation, decreased the number of emboli and reduced the duration of embolization, compared with control (p ≤ 0.05). Of all the studied NSAIDs being injected either with LMWH or separately 30 minutes before the thrombosis stimulation by LASER only Aspirin appeared to potentiate the antithrombotic effect of FraxiparineR. Neither LMWH nor NSAIDs (except for Aspirin) at the dosages used modified aggregatory parameters compared with control. But it was observed the inhibition of platelet aggregation by the associations of FraxiparineR with Aspirin, FeldeneR or ProfenidR, tested in the whole blood 90 minutes after the drug injections." @default.
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- W1970861895 date "1995-02-01" @default.
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- W1970861895 title "Effect of the low molecular weight heparin/non steroidal antiinflammatory drugs association on an experimental thrombosis induced by laser" @default.
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- W1970861895 doi "https://doi.org/10.1016/0049-3848(95)93834-m" @default.
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