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- W1970869929 abstract "Cancer chemoprevention, which is defined as the use of natural or synthetic chemical agents to reverse or suppress carcinogenic processes, is an important strategy to reduce the risk of cancer. Many laboratory studies have suggested beneficial effects of various dietary compounds (phytochemicals) in reducing the risk of cancer. Apoptosis (programmed cell death) plays a critical role in normal physiological functions, but there is a dysregulation of apoptosis in cancer as well as in other chronic diseases, such as neurodegenerative disorders. Many natural cancer chemopreventive compounds are known to induce apoptosis. At the molecular level, dietary chemopreventive compounds can modulate a number of key elements of cell signal transduction pathways involved in the apoptotic process. This review stresses the importance of apoptosis induction by natural dietary agents for cancer chemoprevention." @default.
- W1970869929 created "2016-06-24" @default.
- W1970869929 creator A5063439535 @default.
- W1970869929 date "2013-06-01" @default.
- W1970869929 modified "2023-10-05" @default.
- W1970869929 title "Role of Apoptosis in the Chemoprevention of Cancer" @default.
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- W1970869929 doi "https://doi.org/10.1016/j.jecm.2013.04.001" @default.
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