FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970879501> ?p ?o ?g. }

• W1970879501 endingPage "1965" @default.
• W1970879501 startingPage "1957" @default.
• W1970879501 abstract "Inverted urothelial papilloma (IUP) is an uncommon neoplasm of the urinary bladder with distinct morphologic features. Studies regarding the role of human papillomavirus (HPV) in the etiology of IUP have provided conflicting evidence of HPV infection. In addition, little is known regarding the molecular alterations present in IUP or other urothelial neoplasms, which might demonstrate inverted growth pattern like low-grade or high-grade urothelial carcinoma (UCA). Here, we evaluated for the presence of common driving somatic mutations and HPV within a cohort of IUPs, (n = 7) noninvasive low-grade papillary UCAs with inverted growth pattern (n = 5), and noninvasive high-grade papillary UCAs with inverted growth pattern (n = 8). HPV was not detected in any case of IUP or inverted UCA by either in situ hybridization or by polymerase chain reaction. Next-generation sequencing identified recurrent mutations in HRAS (Q61R) in 3 of 5 IUPs, described for the first time in this neoplasm. Additional mutations of Ras pathway members were detected including HRAS, KRAS, and BRAF. The presence of Ras pathway member mutations at a relatively high rate suggests this pathway may contribute to pathogenesis of inverted urothelial neoplasms. In addition, we did not find any evidence supporting a role for HPV in the etiology of IUP." @default.
• W1970879501 created "2016-06-24" @default.
• W1970879501 creator A5003311852 @default.
• W1970879501 creator A5018208869 @default.
• W1970879501 creator A5027920712 @default.
• W1970879501 creator A5031784645 @default.
• W1970879501 creator A5032617990 @default.
• W1970879501 creator A5035266638 @default.
• W1970879501 creator A5044876102 @default.
• W1970879501 creator A5056372279 @default.
• W1970879501 creator A5060849370 @default.
• W1970879501 creator A5063597545 @default.
• W1970879501 creator A5068238406 @default.
• W1970879501 creator A5068922056 @default.
• W1970879501 creator A5073368743 @default.
• W1970879501 creator A5083968353 @default.
• W1970879501 creator A5089805603 @default.
• W1970879501 creator A5090234957 @default.
• W1970879501 date "2014-09-01" @default.
• W1970879501 modified "2023-09-25" @default.
• W1970879501 title "HRAS mutations are frequent in inverted urothelial neoplasms" @default.
• W1970879501 cites W1480329487 @default.
• W1970879501 cites W1881808103 @default.
• W1970879501 cites W1969722039 @default.
• W1970879501 cites W1971132223 @default.
• W1970879501 cites W1975004069 @default.
• W1970879501 cites W1975013621 @default.
• W1970879501 cites W1976487526 @default.
• W1970879501 cites W1988863397 @default.
• W1970879501 cites W1992526215 @default.
• W1970879501 cites W1995989976 @default.
• W1970879501 cites W2019724785 @default.
• W1970879501 cites W2022944504 @default.
• W1970879501 cites W2026347115 @default.
• W1970879501 cites W2037340955 @default.
• W1970879501 cites W2037959814 @default.
• W1970879501 cites W2041277175 @default.
• W1970879501 cites W2059166270 @default.
• W1970879501 cites W2068523052 @default.
• W1970879501 cites W2069287896 @default.
• W1970879501 cites W2087360479 @default.
• W1970879501 cites W2089140761 @default.
• W1970879501 cites W2095024711 @default.
• W1970879501 cites W2095544527 @default.
• W1970879501 cites W2117197109 @default.
• W1970879501 cites W2129215988 @default.
• W1970879501 cites W2135687675 @default.
• W1970879501 cites W2136911450 @default.
• W1970879501 cites W2143686852 @default.
• W1970879501 cites W2144609587 @default.
• W1970879501 cites W2150283099 @default.
• W1970879501 cites W2169250920 @default.
• W1970879501 cites W2329181419 @default.
• W1970879501 cites W2987290872 @default.
• W1970879501 cites W96160172 @default.
• W1970879501 doi "https://doi.org/10.1016/j.humpath.2014.06.003" @default.
• W1970879501 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4241848" @default.
• W1970879501 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25097040" @default.
• W1970879501 hasPublicationYear "2014" @default.
• W1970879501 type Work @default.
• W1970879501 sameAs 1970879501 @default.
• W1970879501 citedByCount "36" @default.
• W1970879501 countsByYear W19708795012015 @default.
• W1970879501 countsByYear W19708795012016 @default.
• W1970879501 countsByYear W19708795012017 @default.
• W1970879501 countsByYear W19708795012018 @default.
• W1970879501 countsByYear W19708795012019 @default.
• W1970879501 countsByYear W19708795012020 @default.
• W1970879501 countsByYear W19708795012021 @default.
• W1970879501 countsByYear W19708795012022 @default.
• W1970879501 countsByYear W19708795012023 @default.
• W1970879501 crossrefType "journal-article" @default.
• W1970879501 hasAuthorship W1970879501A5003311852 @default.
• W1970879501 hasAuthorship W1970879501A5018208869 @default.
• W1970879501 hasAuthorship W1970879501A5027920712 @default.
• W1970879501 hasAuthorship W1970879501A5031784645 @default.
• W1970879501 hasAuthorship W1970879501A5032617990 @default.
• W1970879501 hasAuthorship W1970879501A5035266638 @default.
• W1970879501 hasAuthorship W1970879501A5044876102 @default.
• W1970879501 hasAuthorship W1970879501A5056372279 @default.
• W1970879501 hasAuthorship W1970879501A5060849370 @default.
• W1970879501 hasAuthorship W1970879501A5063597545 @default.
• W1970879501 hasAuthorship W1970879501A5068238406 @default.
• W1970879501 hasAuthorship W1970879501A5068922056 @default.
• W1970879501 hasAuthorship W1970879501A5073368743 @default.
• W1970879501 hasAuthorship W1970879501A5083968353 @default.
• W1970879501 hasAuthorship W1970879501A5089805603 @default.
• W1970879501 hasAuthorship W1970879501A5090234957 @default.
• W1970879501 hasBestOaLocation W19708795012 @default.
• W1970879501 hasConcept C104317684 @default.
• W1970879501 hasConcept C1167327 @default.
• W1970879501 hasConcept C121608353 @default.
• W1970879501 hasConcept C142724271 @default.
• W1970879501 hasConcept C2776270601 @default.
• W1970879501 hasConcept C2776350393 @default.
• W1970879501 hasConcept C2778220009 @default.
• W1970879501 hasConcept C2779317333 @default.
• W1970879501 hasConcept C2781187634 @default.

• next