FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970889384> ?p ?o ?g. }

• W1970889384 endingPage "e113945" @default.
• W1970889384 startingPage "e113945" @default.
• W1970889384 abstract "The autonomic nervous system plays an important role in rat anaphylactic hypotension. It is well known that sympathetic nerve activity and cardiovascular function are affected by anesthetics. However, the effects of different types of anesthesia on the efferent renal sympathetic nerve activity (RSNA) during anaphylactic hypotension remain unknown. Therefore, we determined the renal sympathetic responses to anaphylactic hypotension in anesthetized and conscious rats and the roles of baroreceptors in these responses. Sprague-Dawley rats were randomly allocated to anesthetic groups that were given pentobarbital, urethane, or ketamine-xylazine and to a conscious group. The rats were sensitized using subcutaneously injected ovalbumin. The systemic arterial pressure (SAP), RSNA and heart rate (HR) were measured. The effects of sinoaortic baroreceptor denervation on RSNA during anaphylaxis were determined in pentobarbital-anesthetized and conscious rats. In all of the sensitized rats, the RSNA increased and SAP decreased after antigen injection. At the early phase within 35 min of the antigen injection, the antigen-induced sympathoexcitation in the conscious rats was significantly greater than that in the anesthetized rats. Anaphylactic hypotension was attenuated in the conscious rats compared to the anesthetized rats. The anesthetic-induced suppression of SAP and RSNA was greater in the order ketamine-xylazine >urethane = pentobarbital. Indeed, in the rats treated with ketamine-xylazine, RSNA did not increase until 40 min, and SAP remained at low levels after the antigen injection. The baroreceptor reflex, as evaluated by increases in RSNA and HR in response to the decrease in SAP induced by sodium nitroprusside (SNP), was suppressed in the anesthetized rats compared with the conscious rats. Consistent with this finding, baroreceptor denervation attenuated the excitatory responses of RSNA to anaphylaxis in the conscious rats but not in the pentobarbital-anesthetized rats. RSNA was increased markedly in conscious rats during anaphylactic hypotension. Anesthetics attenuated this antigen-induced renal sympathoexcitation through the suppression of baroreceptor function." @default.
• W1970889384 created "2016-06-24" @default.
• W1970889384 creator A5001319955 @default.
• W1970889384 creator A5037148874 @default.
• W1970889384 creator A5056982994 @default.
• W1970889384 creator A5065064934 @default.
• W1970889384 creator A5069754727 @default.
• W1970889384 creator A5084794906 @default.
• W1970889384 date "2014-11-25" @default.
• W1970889384 modified "2023-09-26" @default.
• W1970889384 title "Effects of Anesthetics on the Renal Sympathetic Response to Anaphylactic Hypotension in Rats" @default.
• W1970889384 cites W1555493494 @default.
• W1970889384 cites W1595208411 @default.
• W1970889384 cites W1850097441 @default.
• W1970889384 cites W1963857091 @default.
• W1970889384 cites W1992936313 @default.
• W1970889384 cites W1994756986 @default.
• W1970889384 cites W1998723097 @default.
• W1970889384 cites W1999900565 @default.
• W1970889384 cites W2001861506 @default.
• W1970889384 cites W2014553522 @default.
• W1970889384 cites W2021195835 @default.
• W1970889384 cites W2024328209 @default.
• W1970889384 cites W2033296311 @default.
• W1970889384 cites W2038502532 @default.
• W1970889384 cites W2041579335 @default.
• W1970889384 cites W2046926887 @default.
• W1970889384 cites W2086092998 @default.
• W1970889384 cites W2094616997 @default.
• W1970889384 cites W2107318205 @default.
• W1970889384 cites W2115490015 @default.
• W1970889384 cites W2124118232 @default.
• W1970889384 cites W2127655000 @default.
• W1970889384 cites W2150341119 @default.
• W1970889384 cites W2182680155 @default.
• W1970889384 cites W2274998399 @default.
• W1970889384 cites W2368065545 @default.
• W1970889384 cites W2423115156 @default.
• W1970889384 doi "https://doi.org/10.1371/journal.pone.0113945" @default.
• W1970889384 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4244183" @default.
• W1970889384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25423366" @default.
• W1970889384 hasPublicationYear "2014" @default.
• W1970889384 type Work @default.
• W1970889384 sameAs 1970889384 @default.
• W1970889384 citedByCount "9" @default.
• W1970889384 countsByYear W19708893842015 @default.
• W1970889384 countsByYear W19708893842016 @default.
• W1970889384 countsByYear W19708893842017 @default.
• W1970889384 countsByYear W19708893842018 @default.
• W1970889384 countsByYear W19708893842019 @default.
• W1970889384 countsByYear W19708893842020 @default.
• W1970889384 countsByYear W19708893842022 @default.
• W1970889384 crossrefType "journal-article" @default.
• W1970889384 hasAuthorship W1970889384A5001319955 @default.
• W1970889384 hasAuthorship W1970889384A5037148874 @default.
• W1970889384 hasAuthorship W1970889384A5056982994 @default.
• W1970889384 hasAuthorship W1970889384A5065064934 @default.
• W1970889384 hasAuthorship W1970889384A5069754727 @default.
• W1970889384 hasAuthorship W1970889384A5084794906 @default.
• W1970889384 hasBestOaLocation W19708893841 @default.
• W1970889384 hasConcept C126322002 @default.
• W1970889384 hasConcept C134018914 @default.
• W1970889384 hasConcept C203014093 @default.
• W1970889384 hasConcept C207480886 @default.
• W1970889384 hasConcept C2775933838 @default.
• W1970889384 hasConcept C2776755955 @default.
• W1970889384 hasConcept C2777953023 @default.
• W1970889384 hasConcept C2778162923 @default.
• W1970889384 hasConcept C2779591255 @default.
• W1970889384 hasConcept C2780795376 @default.
• W1970889384 hasConcept C42219234 @default.
• W1970889384 hasConcept C71924100 @default.
• W1970889384 hasConcept C79752029 @default.
• W1970889384 hasConcept C84393581 @default.
• W1970889384 hasConceptScore W1970889384C126322002 @default.
• W1970889384 hasConceptScore W1970889384C134018914 @default.
• W1970889384 hasConceptScore W1970889384C203014093 @default.
• W1970889384 hasConceptScore W1970889384C207480886 @default.
• W1970889384 hasConceptScore W1970889384C2775933838 @default.
• W1970889384 hasConceptScore W1970889384C2776755955 @default.
• W1970889384 hasConceptScore W1970889384C2777953023 @default.
• W1970889384 hasConceptScore W1970889384C2778162923 @default.
• W1970889384 hasConceptScore W1970889384C2779591255 @default.
• W1970889384 hasConceptScore W1970889384C2780795376 @default.
• W1970889384 hasConceptScore W1970889384C42219234 @default.
• W1970889384 hasConceptScore W1970889384C71924100 @default.
• W1970889384 hasConceptScore W1970889384C79752029 @default.
• W1970889384 hasConceptScore W1970889384C84393581 @default.
• W1970889384 hasIssue "11" @default.
• W1970889384 hasLocation W19708893841 @default.
• W1970889384 hasLocation W19708893842 @default.
• W1970889384 hasLocation W19708893843 @default.
• W1970889384 hasLocation W19708893844 @default.
• W1970889384 hasOpenAccess W1970889384 @default.
• W1970889384 hasPrimaryLocation W19708893841 @default.
• W1970889384 hasRelatedWork W162026588 @default.
• W1970889384 hasRelatedWork W1970889384 @default.
• W1970889384 hasRelatedWork W2010261788 @default.

• next