Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970894766> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W1970894766 endingPage "e3" @default.
- W1970894766 startingPage "e1" @default.
- W1970894766 abstract "La recherche de la mutation JAK2 V617F est devenue indispensable au diagnostic des syndromes myéloprolifératifs (SMP). Nous rapportons une observation qui illustre l’intérêt éventuel de sa recherche dans le bilan de thrombophilie en cas de thrombose veineuse profonde des membres inférieurs (TVPMI). Un homme de 73 ans présentait trois épisodes de thrombose veineuse spontanée, le troisième alors que le patient était sous fluindione. Un hématocrite à 55 % et un taux d’hémoglobine à 17 g/dl faisaient discuter un SMP : le diagnostic de maladie de Vaquez était confirmé par la positivité de la mutation JAK2 V617F et la masse globulaire isotopique. L’intérêt de la recherche de la mutation JAK2 a été clairement démontré pour le diagnostic des SMP. Certaines études ont confirmé l’intérêt de la recherche de cette mutation en cas de thrombose abdominale en apparence idiopathique. Cette observation illustre son intérêt éventuel au cours de TVPMI ambulatoires, inexpliquées et récidivantes, en particulier sous traitement anticoagulant efficace. The search of JAK2 V617F mutation is a useful tool for the diagnosis of myeloproliferative disorders (MPD). This case report highlights the potential usefulness of this testing in recurrent deep venous thrombosis (DVT) of lower limb. We report a 73-year-old man who presented with three spontaneous episodes of lower limb DVT. The third episode occured while he was receiving fluindione. MPD was suspected because of an increased hematocrit (55 %) and hemoglobin (17 g/dl) level. Red cell blood volume was increased and a JAK2 V617F mutation was detected confirming the diagnosis of polycythemia vera. The usefulness of JAK2 mutation for the diagnosis of MPD has been widely demonstrated. Also, some studies confirmed its usefulness in apparently idiopathic abdominal venous thrombosis. This report highlights the possible interest of JAK2 mutation in unexplained recurrent lower limb DVT, especially when it occurs under anticoagulant therapy." @default.
- W1970894766 created "2016-06-24" @default.
- W1970894766 creator A5008317770 @default.
- W1970894766 creator A5025863070 @default.
- W1970894766 creator A5029546202 @default.
- W1970894766 creator A5050732278 @default.
- W1970894766 creator A5064217775 @default.
- W1970894766 creator A5082792801 @default.
- W1970894766 creator A5083557940 @default.
- W1970894766 date "2010-07-01" @default.
- W1970894766 modified "2023-10-01" @default.
- W1970894766 title "La recherche de la mutation JAK2 peut-elle être utile dans le bilan étiologique d’une maladie thromboembolique récidivante ?" @default.
- W1970894766 cites W1549228081 @default.
- W1970894766 cites W1966545466 @default.
- W1970894766 cites W1968802616 @default.
- W1970894766 cites W1992030781 @default.
- W1970894766 cites W1992746829 @default.
- W1970894766 cites W1993230181 @default.
- W1970894766 cites W1994415676 @default.
- W1970894766 cites W2000429990 @default.
- W1970894766 cites W2026393800 @default.
- W1970894766 cites W2026965552 @default.
- W1970894766 cites W2079805136 @default.
- W1970894766 cites W2109685371 @default.
- W1970894766 cites W2138524652 @default.
- W1970894766 doi "https://doi.org/10.1016/j.revmed.2009.05.014" @default.
- W1970894766 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20362361" @default.
- W1970894766 hasPublicationYear "2010" @default.
- W1970894766 type Work @default.
- W1970894766 sameAs 1970894766 @default.
- W1970894766 citedByCount "1" @default.
- W1970894766 crossrefType "journal-article" @default.
- W1970894766 hasAuthorship W1970894766A5008317770 @default.
- W1970894766 hasAuthorship W1970894766A5025863070 @default.
- W1970894766 hasAuthorship W1970894766A5029546202 @default.
- W1970894766 hasAuthorship W1970894766A5050732278 @default.
- W1970894766 hasAuthorship W1970894766A5064217775 @default.
- W1970894766 hasAuthorship W1970894766A5082792801 @default.
- W1970894766 hasAuthorship W1970894766A5083557940 @default.
- W1970894766 hasConcept C29456083 @default.
- W1970894766 hasConcept C71924100 @default.
- W1970894766 hasConceptScore W1970894766C29456083 @default.
- W1970894766 hasConceptScore W1970894766C71924100 @default.
- W1970894766 hasIssue "7" @default.
- W1970894766 hasLocation W19708947661 @default.
- W1970894766 hasLocation W19708947662 @default.
- W1970894766 hasOpenAccess W1970894766 @default.
- W1970894766 hasPrimaryLocation W19708947661 @default.
- W1970894766 hasRelatedWork W1506200166 @default.
- W1970894766 hasRelatedWork W1995515455 @default.
- W1970894766 hasRelatedWork W1999344589 @default.
- W1970894766 hasRelatedWork W2039318446 @default.
- W1970894766 hasRelatedWork W2080531066 @default.
- W1970894766 hasRelatedWork W2748952813 @default.
- W1970894766 hasRelatedWork W2789448498 @default.
- W1970894766 hasRelatedWork W2899084033 @default.
- W1970894766 hasRelatedWork W3032375762 @default.
- W1970894766 hasRelatedWork W3108674512 @default.
- W1970894766 hasVolume "31" @default.
- W1970894766 isParatext "false" @default.
- W1970894766 isRetracted "false" @default.
- W1970894766 magId "1970894766" @default.
- W1970894766 workType "article" @default.