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• W1970944891 abstract "The relative lipophilicity of ten non-steroidal anti-inflammatory agents have been determined by reversed-phase thin layer chromatography using different reversed-phase high-performance thin-layer chromatography plates and water-methanol mixtures as eluents. The compounds studied showed regular retention behavior, their RM values decreasing linearly with increasing concentration of methanol in the eluent. Principal component analysis allowed a more rational and objective estimation and comparison of lipophilicity determined by reversed-phase thin-layer chromatography. It also affords a useful graphical tool, since scatterplots of the scores onto the plane described by the first two components will have the effect of separating compounds from each other most effectively, thus obtaining congeneric lipophilicity chart." @default.
• W1970944891 created "2016-06-24" @default.
• W1970944891 creator A5041210785 @default.
• W1970944891 creator A5047205618 @default.
• W1970944891 date "1998-10-01" @default.
• W1970944891 modified "2023-10-17" @default.
• W1970944891 title "Determination of lipophilicity of some non-steroidal anti-inflammatory agents and their relationships by using principal component analysis based on thin-layer chromatographic retention data" @default.
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• W1970944891 doi "https://doi.org/10.1016/s0021-9673(98)00571-8" @default.
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