FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970971339> ?p ?o ?g. }

• W1970971339 endingPage "31" @default.
• W1970971339 startingPage "28" @default.
• W1970971339 abstract "The results of the present study suggest that DmTpc1 is actively implicated in the specific uptake of free cytoplasmic Pt bonded nucleotides, and therefore could be linked to the mechanism of action of some platinum-based antitumor drugs. Although DmTpc1 has a low affinity for model [Pt(dien)(N7-5'-dGTP)] and cis-[Pt(NH3)2(py)(N7-5'-dGTP)] compared to dATP it's well known that DNA platination level of few metal atoms per double-stranded molecule may account for the pharmacological activity of platinum based antitumor drugs. This is the first investigation where it has been demonstrated that a mitochondrial carrier is directly involved in the transport of metalated purines related with the cisplatin mechanism of action. Moreover it is shown as a lower hindrance of nucleotide bonded platinum complexes could strongly enhance mitochondrial uptake. Furthermore, a new application of ICP-AES addressed to measure the transport of metalated nucleobases, by using a recombinant protein reconstituted into liposomes, has been here, for the first time, developed and compared with a standard technique such as the liquid scintillation counting." @default.
• W1970971339 created "2016-06-24" @default.
• W1970971339 creator A5002168845 @default.
• W1970971339 creator A5014579151 @default.
• W1970971339 creator A5018605561 @default.
• W1970971339 creator A5023886888 @default.
• W1970971339 creator A5025177419 @default.
• W1970971339 creator A5027032713 @default.
• W1970971339 creator A5031745185 @default.
• W1970971339 creator A5037169581 @default.
• W1970971339 creator A5056143507 @default.
• W1970971339 date "2014-01-01" @default.
• W1970971339 modified "2023-09-29" @default.
• W1970971339 title "Transport of platinum bonded nucleotides into proteoliposomes, mediated by Drosophila melanogaster thiamine pyrophosphate carrier protein (DmTpc1)" @default.
• W1970971339 cites W1552922487 @default.
• W1970971339 cites W1982029299 @default.
• W1970971339 cites W1999831215 @default.
• W1970971339 cites W2006826463 @default.
• W1970971339 cites W2008245445 @default.
• W1970971339 cites W2012108057 @default.
• W1970971339 cites W2016014642 @default.
• W1970971339 cites W2018187847 @default.
• W1970971339 cites W2025293912 @default.
• W1970971339 cites W2026238002 @default.
• W1970971339 cites W2032853374 @default.
• W1970971339 cites W2045763444 @default.
• W1970971339 cites W2048714785 @default.
• W1970971339 cites W2050703823 @default.
• W1970971339 cites W2054390824 @default.
• W1970971339 cites W2066043469 @default.
• W1970971339 cites W2082902525 @default.
• W1970971339 cites W2089686757 @default.
• W1970971339 cites W2091994392 @default.
• W1970971339 cites W2093301333 @default.
• W1970971339 cites W2095909605 @default.
• W1970971339 cites W2098891794 @default.
• W1970971339 cites W2107153558 @default.
• W1970971339 cites W2144224213 @default.
• W1970971339 cites W2152560836 @default.
• W1970971339 cites W2159919133 @default.
• W1970971339 cites W2323651820 @default.
• W1970971339 doi "https://doi.org/10.1016/j.jinorgbio.2013.09.012" @default.
• W1970971339 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24148759" @default.
• W1970971339 hasPublicationYear "2014" @default.
• W1970971339 type Work @default.
• W1970971339 sameAs 1970971339 @default.
• W1970971339 citedByCount "18" @default.
• W1970971339 countsByYear W19709713392015 @default.
• W1970971339 countsByYear W19709713392016 @default.
• W1970971339 countsByYear W19709713392018 @default.
• W1970971339 countsByYear W19709713392020 @default.
• W1970971339 countsByYear W19709713392021 @default.
• W1970971339 countsByYear W19709713392022 @default.
• W1970971339 countsByYear W19709713392023 @default.
• W1970971339 crossrefType "journal-article" @default.
• W1970971339 hasAuthorship W1970971339A5002168845 @default.
• W1970971339 hasAuthorship W1970971339A5014579151 @default.
• W1970971339 hasAuthorship W1970971339A5018605561 @default.
• W1970971339 hasAuthorship W1970971339A5023886888 @default.
• W1970971339 hasAuthorship W1970971339A5025177419 @default.
• W1970971339 hasAuthorship W1970971339A5027032713 @default.
• W1970971339 hasAuthorship W1970971339A5031745185 @default.
• W1970971339 hasAuthorship W1970971339A5037169581 @default.
• W1970971339 hasAuthorship W1970971339A5056143507 @default.
• W1970971339 hasConcept C104317684 @default.
• W1970971339 hasConcept C11960822 @default.
• W1970971339 hasConcept C12554922 @default.
• W1970971339 hasConcept C161790260 @default.
• W1970971339 hasConcept C178666793 @default.
• W1970971339 hasConcept C181199279 @default.
• W1970971339 hasConcept C181912034 @default.
• W1970971339 hasConcept C185592680 @default.
• W1970971339 hasConcept C197957613 @default.
• W1970971339 hasConcept C202751555 @default.
• W1970971339 hasConcept C2776043855 @default.
• W1970971339 hasConcept C2776120743 @default.
• W1970971339 hasConcept C2776476023 @default.
• W1970971339 hasConcept C2780047943 @default.
• W1970971339 hasConcept C512185932 @default.
• W1970971339 hasConcept C518104683 @default.
• W1970971339 hasConcept C552990157 @default.
• W1970971339 hasConcept C55493867 @default.
• W1970971339 hasConcept C71240020 @default.
• W1970971339 hasConcept C86803240 @default.
• W1970971339 hasConceptScore W1970971339C104317684 @default.
• W1970971339 hasConceptScore W1970971339C11960822 @default.
• W1970971339 hasConceptScore W1970971339C12554922 @default.
• W1970971339 hasConceptScore W1970971339C161790260 @default.
• W1970971339 hasConceptScore W1970971339C178666793 @default.
• W1970971339 hasConceptScore W1970971339C181199279 @default.
• W1970971339 hasConceptScore W1970971339C181912034 @default.
• W1970971339 hasConceptScore W1970971339C185592680 @default.
• W1970971339 hasConceptScore W1970971339C197957613 @default.
• W1970971339 hasConceptScore W1970971339C202751555 @default.
• W1970971339 hasConceptScore W1970971339C2776043855 @default.
• W1970971339 hasConceptScore W1970971339C2776120743 @default.
• W1970971339 hasConceptScore W1970971339C2776476023 @default.
• W1970971339 hasConceptScore W1970971339C2780047943 @default.

• next