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- W1970978605 abstract "The introduction of r II mutations into polynucleotide ligase amber mutants (gene 30) of T4D bacteriophage results in the restoration of phage growth in the nonpermissive host E. coli B. When cells are mixedly infected with r II + -ligase - and r II-ligase - phage, growth is reduced, indicating that the r II mutations are recessive to the r II + alleles. Infection with the r II-ligase - double mutants results in nearly complete restoration of phage DNA synthesis and prevents the extensive degradation of parental phage DNA observed after infection with ligase - single mutants. Similar results are observed when cells are infected with ligase - mutants and chloramphenicol is added five minutes post infection." @default.
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- W1970978605 date "1969-11-01" @default.
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- W1970978605 title "SUPPRESSION OF T4D LIGASE MUTATIONS BY rIIA AND rIIB MUTATIONS" @default.
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- W1970978605 doi "https://doi.org/10.1073/pnas.64.3.897" @default.
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