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- W1971012964 abstract "Positron-emission tomography (PET) is a sensitive technique that can be used to measure drug pharmacokinetics and pharmacodynamics non-invasively in target tissues of patients. Here we focus on the application of this technology to address some of the bottlenecks in drug development, including: elucidation of pathophysiology, evaluation of pharmacokinetics, proof of principle of mechanism, and assessment of efficacy and/or response to therapy." @default.
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- W1971012964 date "2001-03-01" @default.
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- W1971012964 title "In vivo pharmacokinetics and pharmacodynamics in drug development using positron-emission tomography" @default.
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- W1971012964 doi "https://doi.org/10.1016/s1359-6446(01)01684-1" @default.
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