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• W1971014905 endingPage "2028" @default.
• W1971014905 startingPage "2022" @default.
• W1971014905 abstract "The ability to assess the elastic and failure properties of cortical bone at the radial diaphysis has a clinical importance. A new generation of quantitative ultrasound (QUS) devices and peripheral quantitative computed tomography (p-QCT) has been developed to assess non-invasively bone material and structural properties at the distal radius. This anatomical site is characterized by a thin cortical thickness that complicates traditional mechanical testing methods on specimens. Until now, mechanical properties of cortical bone at distal radius (e.g., elastic modulus, yield stress and strain) remain rarely studied probably due to experimental difficulties. The present study introduces an inverse finite-element method strategy to measure the elastic modulus and yield properties of human cortical specimens of the radial diaphysis. Twenty millimeter-thick portions of diaphysis were cut from 40 human radii (ages 45–90) for biomechanical test. Subsequently the same portion was modeled in order to obtain a specimen-specific three dimensional finite-element model (3D-FEM). Longitudinal elastic constants at the apparent level and stress characterizations were performed by coupling mechanical parameters with isotropic linear-elastic simulations. The results indicated that the mean apparent Young's modulus for radial cortical bone was 16 GPa (SD 1.8) and the yield stress was 153 MPa (SD 33). Breaking load was 12,946 N (SD 3644), cortical thickness 2.9 mm (SD 0.6), structural effective strain at the yield (εy=0.0097) and failure (εu=0.0154) load were also calculated. The 3D-FEM strategy described here may help to investigate bone mechanical properties when some difficulties arise from machining mechanical sample." @default.
• W1971014905 created "2016-06-24" @default.
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• W1971014905 date "2007-01-01" @default.
• W1971014905 modified "2023-10-14" @default.
• W1971014905 title "Apparent Young's modulus of human radius using inverse finite-element method" @default.
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• W1971014905 doi "https://doi.org/10.1016/j.jbiomech.2006.09.018" @default.
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