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• W1971030337 abstract "Gap junctions are composed of clusters of intercellular channels that electrotonically and metabolically couple apposing cells. Each channel is formed from the pairing of 2 connexons (or hemichannels), which, in turn, are formed by the assembly of 6 connexin monomers. The mammalian genome comprises almost 2 dozen individual connexin genes, and a surprising number of these genes are actively transcribed in the developing or mature heart. The evolutionary advantage for cardiac gap junction diversity remains uncertain. Here, we consider the nature of this diversity and speculate on potential explanations." @default.
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• W1971030337 date "2012-07-01" @default.
• W1971030337 modified "2023-09-26" @default.
• W1971030337 title "Channeling diversity: Gap junction expression in the heart" @default.
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• W1971030337 doi "https://doi.org/10.1016/j.hrthm.2011.11.040" @default.
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