Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971031244> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1971031244 endingPage "93" @default.
- W1971031244 startingPage "83" @default.
- W1971031244 abstract "The sodium and potassium contents of rat brain cortex slices incubated in bicarbonate medium were measured and the intracellular quantities estimated on the basis of the inulin distribution. Ethanol (109 mM) did not affect the ion content of unstimulated tissue during passive leakage in cold medium or aerobic incubation at 37o C. The effects of ethanol (109 mM), tert. butanol (34 mM) and clomethiazole (0.39 mM) were tested on the response to electrical stimulation (entry of sodium and loss of potassium in the non-inulin space) as well as on the restoration of the ionic gradients occurring after a period of stimulation. All agents selectively inhibited the entry of sodium on stimulation with very little effect on potassium loss. The result is considered compatible with preferential action of the drugs on the activation step of the sodium channel controlling movement of sodium during the excitation cycle, and presumably located on the outside of the membranes. During recovery, no inhibition of sodium expulsion was observed, whereas both alcohols- but not clomethiazole-slightly decreased the accumulation of potassium. Considered together with other observations, this finding suggests a special affinity of ethanol for the potassium binding site in the ion transport system." @default.
- W1971031244 created "2016-06-24" @default.
- W1971031244 creator A5019472314 @default.
- W1971031244 creator A5047246126 @default.
- W1971031244 creator A5079417527 @default.
- W1971031244 creator A5082450953 @default.
- W1971031244 date "1974-05-01" @default.
- W1971031244 modified "2023-10-11" @default.
- W1971031244 title "Effects of Ethanol, tert. Butanol, and Clomethiazole on Net Movements of Sodium and Potassium in Electrically Stimulated Cerebral Tissue" @default.
- W1971031244 cites W1447117365 @default.
- W1971031244 cites W1877873475 @default.
- W1971031244 cites W1982535807 @default.
- W1971031244 cites W1990728049 @default.
- W1971031244 cites W1991882147 @default.
- W1971031244 cites W1994408334 @default.
- W1971031244 cites W1996651364 @default.
- W1971031244 cites W2006090981 @default.
- W1971031244 cites W2008778537 @default.
- W1971031244 cites W2017183270 @default.
- W1971031244 cites W2020285419 @default.
- W1971031244 cites W2041655276 @default.
- W1971031244 cites W2052269052 @default.
- W1971031244 cites W2055830907 @default.
- W1971031244 cites W205755798 @default.
- W1971031244 cites W2101732290 @default.
- W1971031244 cites W2109963077 @default.
- W1971031244 cites W2145861896 @default.
- W1971031244 cites W2316870027 @default.
- W1971031244 cites W2404426883 @default.
- W1971031244 cites W69613843 @default.
- W1971031244 doi "https://doi.org/10.1111/j.1748-1716.1974.tb05660.x" @default.
- W1971031244 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4835715" @default.
- W1971031244 hasPublicationYear "1974" @default.
- W1971031244 type Work @default.
- W1971031244 sameAs 1971031244 @default.
- W1971031244 citedByCount "25" @default.
- W1971031244 crossrefType "journal-article" @default.
- W1971031244 hasAuthorship W1971031244A5019472314 @default.
- W1971031244 hasAuthorship W1971031244A5047246126 @default.
- W1971031244 hasAuthorship W1971031244A5079417527 @default.
- W1971031244 hasAuthorship W1971031244A5082450953 @default.
- W1971031244 hasConcept C126322002 @default.
- W1971031244 hasConcept C178790620 @default.
- W1971031244 hasConcept C185592680 @default.
- W1971031244 hasConcept C24998067 @default.
- W1971031244 hasConcept C2779742124 @default.
- W1971031244 hasConcept C2780161600 @default.
- W1971031244 hasConcept C43617362 @default.
- W1971031244 hasConcept C517785266 @default.
- W1971031244 hasConcept C537181965 @default.
- W1971031244 hasConcept C55493867 @default.
- W1971031244 hasConcept C71924100 @default.
- W1971031244 hasConceptScore W1971031244C126322002 @default.
- W1971031244 hasConceptScore W1971031244C178790620 @default.
- W1971031244 hasConceptScore W1971031244C185592680 @default.
- W1971031244 hasConceptScore W1971031244C24998067 @default.
- W1971031244 hasConceptScore W1971031244C2779742124 @default.
- W1971031244 hasConceptScore W1971031244C2780161600 @default.
- W1971031244 hasConceptScore W1971031244C43617362 @default.
- W1971031244 hasConceptScore W1971031244C517785266 @default.
- W1971031244 hasConceptScore W1971031244C537181965 @default.
- W1971031244 hasConceptScore W1971031244C55493867 @default.
- W1971031244 hasConceptScore W1971031244C71924100 @default.
- W1971031244 hasIssue "1" @default.
- W1971031244 hasLocation W19710312441 @default.
- W1971031244 hasLocation W19710312442 @default.
- W1971031244 hasOpenAccess W1971031244 @default.
- W1971031244 hasPrimaryLocation W19710312441 @default.
- W1971031244 hasRelatedWork W2063855007 @default.
- W1971031244 hasRelatedWork W2112214832 @default.
- W1971031244 hasRelatedWork W2123123125 @default.
- W1971031244 hasRelatedWork W2285794816 @default.
- W1971031244 hasRelatedWork W2314245732 @default.
- W1971031244 hasRelatedWork W2323677139 @default.
- W1971031244 hasRelatedWork W2473215621 @default.
- W1971031244 hasRelatedWork W2614668278 @default.
- W1971031244 hasRelatedWork W2733819444 @default.
- W1971031244 hasRelatedWork W2018302231 @default.
- W1971031244 hasVolume "91" @default.
- W1971031244 isParatext "false" @default.
- W1971031244 isRetracted "false" @default.
- W1971031244 magId "1971031244" @default.
- W1971031244 workType "article" @default.