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- W1971038625 abstract "Our goal was to characterize the angiogenic response following traumatic brain injury (TBI).Western analysis for vascular endothelial growth factor (VEGF) expression, double immunofluorescence labeling of endothelium and vascular endothelial growth factor receptor 2 (VEGFR2), bromodioxyuridine (BrdU) incorporation and measurement of capillary density, were all used to determine the temporal angiogenic response following TBI.The angiogenic factors, VEGF and VEGFR2, increase following trauma. Capillary density increases and BrdU incorporation confirm the presence of newly formed vessels up to 48 hours post-injury.Our results indicated that following TBI, there is a substantial increase in angiogenesis and based on morphologic characterization of BrdU-positive nuclei within the endothelium, we provide evidence for vasculogenesis following injury." @default.
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- W1971038625 date "2007-06-01" @default.
- W1971038625 modified "2023-10-14" @default.
- W1971038625 title "Neovascularization following traumatic brain injury: possible evidence for both angiogenesis and vasculogenesis" @default.
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- W1971038625 doi "https://doi.org/10.1179/016164107x204693" @default.
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