FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971052961> ?p ?o ?g. }

• W1971052961 endingPage "316" @default.
• W1971052961 startingPage "312" @default.
• W1971052961 abstract "SUMMARY Despite advances in our understanding of tumour immunology there is no therapy of proven survival benefit for advanced melanoma. Nevertheless, disease progression is slow in a small proportion of patients with metastatic melanoma, suggesting a contribution to outcome from host factors. Recent data have indicated the importance of the heat shock protein receptor CD91 in immune responses to, and progression of, infectious disease. Here we investigate the relationship between CD91 expression and outcome in malignancy. Rare melanoma patients were recruited with advanced disease that was progressing unusually slowly. CD91 expression on their monocytes was compared with control patients with more typical rapidly advancing metastatic disease. Th1 and Th2 cytokines, as well as innate and adaptive immune subsets, were also measured in the two groups. A significant increase in median CD91 expression levels was observed in slow progressors (P = 0·006). There were no differences in other immune subset markers or inflammatory cytokines. The ability of CD91 to internalize and cross-present tumour antigens through the major histocompatibility complex class I pathway may maintain CD8-positive cytotoxic T cell responses and contribute to slow progression of advanced melanoma." @default.
• W1971052961 created "2016-06-24" @default.
• W1971052961 creator A5006623516 @default.
• W1971052961 creator A5034748028 @default.
• W1971052961 creator A5042312594 @default.
• W1971052961 creator A5063643387 @default.
• W1971052961 creator A5067211956 @default.
• W1971052961 creator A5067606220 @default.
• W1971052961 creator A5079409805 @default.
• W1971052961 date "2004-09-27" @default.
• W1971052961 modified "2023-10-16" @default.
• W1971052961 title "The common heat shock protein receptor CD91 is up-regulated on monocytes of advanced melanoma slow progressors" @default.
• W1971052961 cites W1516697601 @default.
• W1971052961 cites W1585007382 @default.
• W1971052961 cites W1968401667 @default.
• W1971052961 cites W1972486638 @default.
• W1971052961 cites W2001015172 @default.
• W1971052961 cites W2001815433 @default.
• W1971052961 cites W2015293248 @default.
• W1971052961 cites W2023235837 @default.
• W1971052961 cites W2033138894 @default.
• W1971052961 cites W2043047254 @default.
• W1971052961 cites W2048857437 @default.
• W1971052961 cites W2050193276 @default.
• W1971052961 cites W2054626405 @default.
• W1971052961 cites W2068955820 @default.
• W1971052961 cites W2074283639 @default.
• W1971052961 cites W2075589412 @default.
• W1971052961 cites W2097096041 @default.
• W1971052961 cites W2110393497 @default.
• W1971052961 cites W2112530895 @default.
• W1971052961 cites W2112645925 @default.
• W1971052961 cites W2131761283 @default.
• W1971052961 cites W2144745164 @default.
• W1971052961 cites W2155906523 @default.
• W1971052961 cites W2164206375 @default.
• W1971052961 cites W2164773724 @default.
• W1971052961 cites W2275476532 @default.
• W1971052961 cites W2339173512 @default.
• W1971052961 cites W2397550478 @default.
• W1971052961 doi "https://doi.org/10.1111/j.1365-2249.2004.02619.x" @default.
• W1971052961 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1809219" @default.
• W1971052961 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15498042" @default.
• W1971052961 hasPublicationYear "2004" @default.
• W1971052961 type Work @default.
• W1971052961 sameAs 1971052961 @default.
• W1971052961 citedByCount "19" @default.
• W1971052961 countsByYear W19710529612012 @default.
• W1971052961 countsByYear W19710529612013 @default.
• W1971052961 countsByYear W19710529612015 @default.
• W1971052961 countsByYear W19710529612016 @default.
• W1971052961 countsByYear W19710529612018 @default.
• W1971052961 countsByYear W19710529612019 @default.
• W1971052961 countsByYear W19710529612022 @default.
• W1971052961 countsByYear W19710529612023 @default.
• W1971052961 crossrefType "journal-article" @default.
• W1971052961 hasAuthorship W1971052961A5006623516 @default.
• W1971052961 hasAuthorship W1971052961A5034748028 @default.
• W1971052961 hasAuthorship W1971052961A5042312594 @default.
• W1971052961 hasAuthorship W1971052961A5063643387 @default.
• W1971052961 hasAuthorship W1971052961A5067211956 @default.
• W1971052961 hasAuthorship W1971052961A5067606220 @default.
• W1971052961 hasAuthorship W1971052961A5079409805 @default.
• W1971052961 hasBestOaLocation W19710529611 @default.
• W1971052961 hasConcept C104317684 @default.
• W1971052961 hasConcept C126322002 @default.
• W1971052961 hasConcept C147483822 @default.
• W1971052961 hasConcept C154317977 @default.
• W1971052961 hasConcept C167672396 @default.
• W1971052961 hasConcept C202751555 @default.
• W1971052961 hasConcept C203014093 @default.
• W1971052961 hasConcept C205260736 @default.
• W1971052961 hasConcept C207936829 @default.
• W1971052961 hasConcept C2777658100 @default.
• W1971052961 hasConcept C2777701055 @default.
• W1971052961 hasConcept C2779134260 @default.
• W1971052961 hasConcept C2779399171 @default.
• W1971052961 hasConcept C502942594 @default.
• W1971052961 hasConcept C55493867 @default.
• W1971052961 hasConcept C71924100 @default.
• W1971052961 hasConcept C86803240 @default.
• W1971052961 hasConcept C8891405 @default.
• W1971052961 hasConceptScore W1971052961C104317684 @default.
• W1971052961 hasConceptScore W1971052961C126322002 @default.
• W1971052961 hasConceptScore W1971052961C147483822 @default.
• W1971052961 hasConceptScore W1971052961C154317977 @default.
• W1971052961 hasConceptScore W1971052961C167672396 @default.
• W1971052961 hasConceptScore W1971052961C202751555 @default.
• W1971052961 hasConceptScore W1971052961C203014093 @default.
• W1971052961 hasConceptScore W1971052961C205260736 @default.
• W1971052961 hasConceptScore W1971052961C207936829 @default.
• W1971052961 hasConceptScore W1971052961C2777658100 @default.
• W1971052961 hasConceptScore W1971052961C2777701055 @default.
• W1971052961 hasConceptScore W1971052961C2779134260 @default.
• W1971052961 hasConceptScore W1971052961C2779399171 @default.
• W1971052961 hasConceptScore W1971052961C502942594 @default.
• W1971052961 hasConceptScore W1971052961C55493867 @default.
• W1971052961 hasConceptScore W1971052961C71924100 @default.

• next