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- W1971059321 abstract "We reviewed the world literature on solitary fibrous tumors of the central nervous system from August 1996 to July 2011, focusing on both clinicopathological features and diagnostic findings. The anatomical distribution of the 220 cases reported so far reveals that most are intracranial and just over one-fifth are intraspinal. In decreasing frequency, intracranial tumors involve the supratentorial and infratentorial compartments, the pontocerebellar angle, the sellar and parasellar regions, and the cranial nerves. Intraspinal tumors are mainly located in the thoracic and cervical segments. Although most solitary fibrous tumors of the central nervous system are dural based, a small subset presents as subpial, intraparenchymal, intraventricular, or as tumors involving the nerve rootlets with no dural connection. Preoperative imaging and intraoperative findings suggest meningioma, schwannoma or neurofibroma, hemangiopericytoma, or pituitary tumors. Immunohistochemistry is critical to establish a definitive histopathological diagnosis. Vimentin, CD34, BCL2, and CD99 are the most consistently positive markers. The usual histologic type generally behaves in a benign manner if complete removal is achieved. Recurrence is anticipated when resection is subtotal or when the tumor exhibits atypical histology. The proliferative index as assessed by MIB1 labeling is of prognostic significance. Occasionally, tumors featuring conventional morphology may recur, perhaps because of minimal residual disease left behind during surgical extirpation. Rare extracranial metastases and tumor-related deaths are on record. Surgery is the treatment of choice. Stereotactic and external beam radiation therapy may be indicated for postsurgical tumor remnants and for unresectable recurrences. Long-term active surveillance of the patients is mandatory." @default.
- W1971059321 created "2016-06-24" @default.
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- W1971059321 date "2011-09-01" @default.
- W1971059321 modified "2023-10-03" @default.
- W1971059321 title "Solitary Fibrous Tumor of the Central Nervous System" @default.
- W1971059321 cites W13609296 @default.
- W1971059321 cites W147945496 @default.
- W1971059321 cites W1520785129 @default.
- W1971059321 cites W1530637885 @default.
- W1971059321 cites W1556883590 @default.
- W1971059321 cites W156924506 @default.
- W1971059321 cites W1598326179 @default.
- W1971059321 cites W1598637750 @default.
- W1971059321 cites W1600866548 @default.
- W1971059321 cites W1601700773 @default.
- W1971059321 cites W1606584657 @default.
- W1971059321 cites W1686914370 @default.
- W1971059321 cites W1909705443 @default.
- W1971059321 cites W193524879 @default.
- W1971059321 cites W1953423642 @default.
- W1971059321 cites W1965020494 @default.
- W1971059321 cites W1965513527 @default.
- W1971059321 cites W1965570491 @default.
- W1971059321 cites W1965604187 @default.
- W1971059321 cites W1967175751 @default.
- W1971059321 cites W1967646005 @default.
- W1971059321 cites W1967823281 @default.
- W1971059321 cites W1971932672 @default.
- W1971059321 cites W1972664241 @default.
- W1971059321 cites W1973373808 @default.
- W1971059321 cites W1973604441 @default.
- W1971059321 cites W1974648679 @default.
- W1971059321 cites W1976876068 @default.
- W1971059321 cites W1977105364 @default.
- W1971059321 cites W1979080654 @default.
- W1971059321 cites W1980792120 @default.
- W1971059321 cites W1981528424 @default.
- W1971059321 cites W1981851476 @default.
- W1971059321 cites W1982258815 @default.
- W1971059321 cites W1982767986 @default.
- W1971059321 cites W1982834489 @default.
- W1971059321 cites W1983013406 @default.
- W1971059321 cites W1984545317 @default.
- W1971059321 cites W1985403236 @default.
- W1971059321 cites W1986287557 @default.
- W1971059321 cites W1988705069 @default.
- W1971059321 cites W1988879451 @default.
- W1971059321 cites W1991581270 @default.
- W1971059321 cites W1991588706 @default.
- W1971059321 cites W1991777227 @default.
- W1971059321 cites W1997145796 @default.
- W1971059321 cites W1999273590 @default.
- W1971059321 cites W1999421433 @default.
- W1971059321 cites W2004326322 @default.
- W1971059321 cites W2008435421 @default.
- W1971059321 cites W2008633516 @default.
- W1971059321 cites W2008646246 @default.
- W1971059321 cites W2009038598 @default.
- W1971059321 cites W2009869925 @default.
- W1971059321 cites W2011741638 @default.
- W1971059321 cites W2012028669 @default.
- W1971059321 cites W2012294884 @default.
- W1971059321 cites W2012444982 @default.
- W1971059321 cites W2012577817 @default.
- W1971059321 cites W2013061882 @default.
- W1971059321 cites W2013267618 @default.
- W1971059321 cites W2014923872 @default.
- W1971059321 cites W2016143607 @default.
- W1971059321 cites W2017552964 @default.
- W1971059321 cites W2017839418 @default.
- W1971059321 cites W2020638411 @default.
- W1971059321 cites W2022442461 @default.
- W1971059321 cites W2023128861 @default.
- W1971059321 cites W2024802501 @default.
- W1971059321 cites W2025076894 @default.
- W1971059321 cites W2027205462 @default.
- W1971059321 cites W2027299920 @default.
- W1971059321 cites W2027649643 @default.
- W1971059321 cites W2028028908 @default.
- W1971059321 cites W2028801503 @default.
- W1971059321 cites W2029363162 @default.
- W1971059321 cites W2029616785 @default.
- W1971059321 cites W2029946901 @default.
- W1971059321 cites W2029989682 @default.
- W1971059321 cites W2030946423 @default.
- W1971059321 cites W2031132944 @default.
- W1971059321 cites W2034311677 @default.