Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971069673> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W1971069673 endingPage "114???124" @default.
- W1971069673 startingPage "114???124" @default.
- W1971069673 abstract "Biochemical, histologic, and immunohistochemical analyses were performed on 34 interface membranes obtained from 33 patients during revision total knee arthroplasty. The membranes had surrounded components of cementless (n = 11) and cemented (n = 23) knee prostheses that were aseptically loose. None of these implant failures was caused by catastrophic polyethylene erosion leading to metal-to-metal contact. The histologic findings were similar in the membranes from cemented and cementless knee components: small polyethylene debris within macrophages and large birefringent polyethylene debris within foreign-body giant cells. Metallic debris was seen in membranes from both groups, but cemented membranes had more polymethylmethacrylate particles and more hyalinization. Intracytoplasmic asteroid bodies were observed in several foreign-body giant cells in both types of membranes. No significant differences were found between the two groups in levels of collagenase, prostaglandin E2 (PGE2), interleukin-1 (IL-1), interleukin-6 (IL-6), or tumor necrosis factor-alpha (TNF-alpha), nor in the population of inflammatory cells stained with IL-1, IL-6, and TNF-alpha antibodies. Membranes that had surrounded components with radiographic evidence of diffuse or localized periprosthetic bone loss released significantly more collagenase, IL-1, IL-6, and TNF than did membranes from components without bone loss. These two groups, however, did not have significantly different PGE2 levels. These findings suggest that polyethylene and metal debris may play a role in macrophage activation and the release of mediators of bone resorption in the membranes surrounding failed cemented and cementless total knee implants." @default.
- W1971069673 created "2016-06-24" @default.
- W1971069673 creator A5001845205 @default.
- W1971069673 creator A5008742394 @default.
- W1971069673 creator A5011770179 @default.
- W1971069673 creator A5019234137 @default.
- W1971069673 creator A5070348443 @default.
- W1971069673 date "1994-02-01" @default.
- W1971069673 modified "2023-10-17" @default.
- W1971069673 title "A Biochemical, Histologic, and Immunohistologic Analysis of Membranes Obtained From Failed Cemented and Cementless Total Knee Arthroplasty" @default.
- W1971069673 doi "https://doi.org/10.1097/00003086-199402000-00015" @default.
- W1971069673 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8119005" @default.
- W1971069673 hasPublicationYear "1994" @default.
- W1971069673 type Work @default.
- W1971069673 sameAs 1971069673 @default.
- W1971069673 citedByCount "51" @default.
- W1971069673 countsByYear W19710696732012 @default.
- W1971069673 countsByYear W19710696732013 @default.
- W1971069673 countsByYear W19710696732014 @default.
- W1971069673 countsByYear W19710696732015 @default.
- W1971069673 countsByYear W19710696732019 @default.
- W1971069673 countsByYear W19710696732023 @default.
- W1971069673 crossrefType "journal-article" @default.
- W1971069673 hasAuthorship W1971069673A5001845205 @default.
- W1971069673 hasAuthorship W1971069673A5008742394 @default.
- W1971069673 hasAuthorship W1971069673A5011770179 @default.
- W1971069673 hasAuthorship W1971069673A5019234137 @default.
- W1971069673 hasAuthorship W1971069673A5070348443 @default.
- W1971069673 hasConcept C108657112 @default.
- W1971069673 hasConcept C126322002 @default.
- W1971069673 hasConcept C141071460 @default.
- W1971069673 hasConcept C142724271 @default.
- W1971069673 hasConcept C185592680 @default.
- W1971069673 hasConcept C2777956040 @default.
- W1971069673 hasConcept C2778120723 @default.
- W1971069673 hasConcept C2778336525 @default.
- W1971069673 hasConcept C2778715743 @default.
- W1971069673 hasConcept C2780554211 @default.
- W1971069673 hasConcept C2781282405 @default.
- W1971069673 hasConcept C2781411149 @default.
- W1971069673 hasConcept C41625074 @default.
- W1971069673 hasConcept C55493867 @default.
- W1971069673 hasConcept C673006 @default.
- W1971069673 hasConcept C71924100 @default.
- W1971069673 hasConceptScore W1971069673C108657112 @default.
- W1971069673 hasConceptScore W1971069673C126322002 @default.
- W1971069673 hasConceptScore W1971069673C141071460 @default.
- W1971069673 hasConceptScore W1971069673C142724271 @default.
- W1971069673 hasConceptScore W1971069673C185592680 @default.
- W1971069673 hasConceptScore W1971069673C2777956040 @default.
- W1971069673 hasConceptScore W1971069673C2778120723 @default.
- W1971069673 hasConceptScore W1971069673C2778336525 @default.
- W1971069673 hasConceptScore W1971069673C2778715743 @default.
- W1971069673 hasConceptScore W1971069673C2780554211 @default.
- W1971069673 hasConceptScore W1971069673C2781282405 @default.
- W1971069673 hasConceptScore W1971069673C2781411149 @default.
- W1971069673 hasConceptScore W1971069673C41625074 @default.
- W1971069673 hasConceptScore W1971069673C55493867 @default.
- W1971069673 hasConceptScore W1971069673C673006 @default.
- W1971069673 hasConceptScore W1971069673C71924100 @default.
- W1971069673 hasLocation W19710696731 @default.
- W1971069673 hasLocation W19710696732 @default.
- W1971069673 hasOpenAccess W1971069673 @default.
- W1971069673 hasPrimaryLocation W19710696731 @default.
- W1971069673 hasRelatedWork W1851135258 @default.
- W1971069673 hasRelatedWork W1964171125 @default.
- W1971069673 hasRelatedWork W2042681077 @default.
- W1971069673 hasRelatedWork W2074513640 @default.
- W1971069673 hasRelatedWork W2092339321 @default.
- W1971069673 hasRelatedWork W2254180632 @default.
- W1971069673 hasRelatedWork W2791767211 @default.
- W1971069673 hasRelatedWork W2920348808 @default.
- W1971069673 hasRelatedWork W2945777973 @default.
- W1971069673 hasRelatedWork W2496514587 @default.
- W1971069673 hasVolume "299" @default.
- W1971069673 isParatext "false" @default.
- W1971069673 isRetracted "false" @default.
- W1971069673 magId "1971069673" @default.
- W1971069673 workType "article" @default.