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- W1971089257 startingPage "63" @default.
- W1971089257 abstract "In selected patients, noninvasive positive pressure ventilation (NIPPV) with a facemask is now commonly employed as the first choice for providing mechanical ventilation in the intensive care unit (ICU). Aerosol therapy for treatment of acute or acute-on-chronic respiratory failure in this setting may be delivered by pressurized metered-dose inhaler (pMDI) with a chamber spacer and facemask or nebulizer and facemask. This article reviews the host of factors influencing aerosol delivery with these devices during NIPPV. These factors include (1) the type of ventilator, (2) mode of ventilation, (3) circuit conditions, (4) type of interface, (5) type of aerosol generator, (6) drug-related factors, (7) breathing parameters, and (8) patient-related factors. Despite the impediments to efficient aerosol delivery because of continuous gas flow, high inspiratory flow rates, air leaks, circuit humidity, and patient-ventilator asynchrony, significant therapeutic effects are achieved after inhaled bronchodilator administration to patients with asthma and chronic obstructive pulmonary disease. Similarly to invasive mechanical ventilation, careful attention to the technique of drug administration is required to optimize therapeutic effects of inhaled therapies during NIPPV. Assessment of the patient's ability to tolerate a facemask, the level of respiratory distress, hemodynamic status, and synchronization of aerosol generation with inspiratory airflow are important factors contributing to the success of aerosol delivery during NIPPV. Further research into novel delivery methods, such as the use of NIPPV with nasal cannulae, could enhance the efficiency, ease of use, and reproducibility of inhalation therapy during noninvasive ventilation." @default.
- W1971089257 created "2016-06-24" @default.
- W1971089257 creator A5073518693 @default.
- W1971089257 date "2012-04-01" @default.
- W1971089257 modified "2023-09-27" @default.
- W1971089257 title "Aerosol Therapy in Patients Receiving Noninvasive Positive Pressure Ventilation" @default.
- W1971089257 cites W1501569192 @default.
- W1971089257 cites W1593633434 @default.
- W1971089257 cites W1830453612 @default.
- W1971089257 cites W1833382012 @default.
- W1971089257 cites W1843845105 @default.
- W1971089257 cites W1854847211 @default.
- W1971089257 cites W1965865248 @default.
- W1971089257 cites W1968056860 @default.
- W1971089257 cites W1968760892 @default.
- W1971089257 cites W1970963931 @default.
- W1971089257 cites W1972949678 @default.
- W1971089257 cites W1973723734 @default.
- W1971089257 cites W1973972675 @default.
- W1971089257 cites W1974576928 @default.
- W1971089257 cites W1975135594 @default.
- W1971089257 cites W1975299301 @default.
- W1971089257 cites W1977130791 @default.
- W1971089257 cites W1982256946 @default.
- W1971089257 cites W1982862133 @default.
- W1971089257 cites W1983105662 @default.
- W1971089257 cites W1986096796 @default.
- W1971089257 cites W1986186916 @default.
- W1971089257 cites W1990369846 @default.
- W1971089257 cites W1990661303 @default.
- W1971089257 cites W1993253950 @default.
- W1971089257 cites W1996139638 @default.
- W1971089257 cites W1998792586 @default.
- W1971089257 cites W1998833950 @default.
- W1971089257 cites W1999631470 @default.
- W1971089257 cites W2002497517 @default.
- W1971089257 cites W2004695976 @default.
- W1971089257 cites W2005333284 @default.
- W1971089257 cites W2008706179 @default.
- W1971089257 cites W2010239256 @default.
- W1971089257 cites W2012688625 @default.
- W1971089257 cites W2013988543 @default.
- W1971089257 cites W2015466335 @default.
- W1971089257 cites W2018809064 @default.
- W1971089257 cites W2019376803 @default.
- W1971089257 cites W2021000942 @default.
- W1971089257 cites W2023305713 @default.
- W1971089257 cites W2026569302 @default.
- W1971089257 cites W2030446172 @default.
- W1971089257 cites W2035277220 @default.
- W1971089257 cites W2037995141 @default.
- W1971089257 cites W2039910993 @default.
- W1971089257 cites W2040687558 @default.
- W1971089257 cites W2046085450 @default.
- W1971089257 cites W2047417898 @default.
- W1971089257 cites W2048091641 @default.
- W1971089257 cites W2048876877 @default.
- W1971089257 cites W2053041839 @default.
- W1971089257 cites W2053557804 @default.
- W1971089257 cites W2055094574 @default.
- W1971089257 cites W2057827167 @default.
- W1971089257 cites W2062811430 @default.
- W1971089257 cites W2063756800 @default.
- W1971089257 cites W2067131425 @default.
- W1971089257 cites W2074726334 @default.
- W1971089257 cites W2075647822 @default.
- W1971089257 cites W2079682800 @default.
- W1971089257 cites W2083561704 @default.
- W1971089257 cites W2084257990 @default.
- W1971089257 cites W2086313465 @default.
- W1971089257 cites W2086387240 @default.
- W1971089257 cites W2086942174 @default.
- W1971089257 cites W2088557343 @default.
- W1971089257 cites W2089182835 @default.
- W1971089257 cites W2090363402 @default.
- W1971089257 cites W2094188565 @default.
- W1971089257 cites W2095863570 @default.
- W1971089257 cites W2096426156 @default.
- W1971089257 cites W2097590575 @default.
- W1971089257 cites W2097973957 @default.
- W1971089257 cites W2101909755 @default.
- W1971089257 cites W2102010268 @default.
- W1971089257 cites W2102718946 @default.
- W1971089257 cites W2103800887 @default.
- W1971089257 cites W2104467281 @default.
- W1971089257 cites W2105136542 @default.
- W1971089257 cites W2108176324 @default.
- W1971089257 cites W2111507805 @default.
- W1971089257 cites W2112603129 @default.
- W1971089257 cites W2116777337 @default.
- W1971089257 cites W2119444787 @default.
- W1971089257 cites W2119905253 @default.
- W1971089257 cites W2122744323 @default.
- W1971089257 cites W2128921798 @default.
- W1971089257 cites W2135502040 @default.
- W1971089257 cites W2136304412 @default.
- W1971089257 cites W2139123153 @default.
- W1971089257 cites W2141436328 @default.