FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971089452> ?p ?o ?g. }

• W1971089452 endingPage "516" @default.
• W1971089452 startingPage "509" @default.
• W1971089452 abstract "Platelet dysfunction is the most common cause of nonsurgical bleeding after cardiopulmonary bypass (CPB). We hypothesized that reinfusion of a therapeutic quantity of platelets sequestered before CPB would decrease the need for allogeneic platelet transfusion, as well as decrease bleeding and total allogeneic transfusion, in cardiac surgery patients at moderately high risk for bleeding. Fifty-five patients undergoing either reoperative coronary artery bypass (CABG) or combined CABG and valve replacement were randomized to control or platelet-rich plasma sequestration (pheresis) groups. All patients received intraoperative epsilon-aminocaproic acid infusions. There was no significant difference between groups with respect to preoperative characteristics, duration of CPB, or target postoperative hematocrit. Mean platelet yields were 6.2 +/- 2.1 units (3.1 x 10(11) platelets). Mean pheresis time was 44 min. Allogeneic platelets (range = 6-12 units) were transfused to 28% of control patients, compared with 0% of pheresis patients (P < 0.01). Allogeneic packed red blood cells were transfused to 45% of control patients (1.2 units per patient) versus 31% of pheresis patients (0. 7 unit per patient) (P = 0.35). Total allogeneic units transfused were significantly reduced in the pheresis group (P < 0.02). Mediastinal chest tube drainage was not significantly decreased in the pheresis group. In this prospective, randomized study, therapeutic platelet yields were obtained before CPB. In contrast with recent studies with low platelet yields, these data support the conclusion that platelet-rich plasma sequestration is effective in reducing allogeneic platelet transfusions and total allogeneic units transfused in cardiac surgery patients at moderately high risk for post-CPB coagulopathy and bleeding.Transfusion of allogeneic blood products, including platelets, is common during complex cardiac surgical procedures. In the present prospective, randomized study, a significant reduction in allogeneic platelet transfusion and total allogeneic units transfused was observed after the reinfusion of a therapeutic quantity of autologous platelets sequestered before cardiopulmonary bypass." @default.
• W1971089452 created "2016-06-24" @default.
• W1971089452 creator A5048202574 @default.
• W1971089452 creator A5055295106 @default.
• W1971089452 creator A5062514178 @default.
• W1971089452 creator A5063007213 @default.
• W1971089452 creator A5085008271 @default.
• W1971089452 date "2000-03-01" @default.
• W1971089452 modified "2023-10-18" @default.
• W1971089452 title "Platelet-Rich Plasma Sequestration, with Therapeutic Platelet Yields, Reduces Allogeneic Transfusion in Complex Cardiac Surgery" @default.
• W1971089452 cites W1973589575 @default.
• W1971089452 cites W1982092198 @default.
• W1971089452 cites W2037345278 @default.
• W1971089452 cites W2057646315 @default.
• W1971089452 cites W2075287186 @default.
• W1971089452 cites W2078171732 @default.
• W1971089452 cites W2086083152 @default.
• W1971089452 cites W2088592005 @default.
• W1971089452 cites W2092064375 @default.
• W1971089452 cites W2105100188 @default.
• W1971089452 cites W2105389614 @default.
• W1971089452 cites W2152028587 @default.
• W1971089452 cites W2153435025 @default.
• W1971089452 cites W2397183867 @default.
• W1971089452 cites W2405062203 @default.
• W1971089452 cites W2415793947 @default.
• W1971089452 cites W2917977019 @default.
• W1971089452 cites W2993672760 @default.
• W1971089452 cites W4232977483 @default.
• W1971089452 cites W4241842482 @default.
• W1971089452 cites W4250866529 @default.
• W1971089452 cites W4293915724 @default.
• W1971089452 cites W50257404 @default.
• W1971089452 doi "https://doi.org/10.1097/00000539-200003000-00002" @default.
• W1971089452 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10702428" @default.
• W1971089452 hasPublicationYear "2000" @default.
• W1971089452 type Work @default.
• W1971089452 sameAs 1971089452 @default.
• W1971089452 citedByCount "44" @default.
• W1971089452 countsByYear W19710894522012 @default.
• W1971089452 countsByYear W19710894522013 @default.
• W1971089452 countsByYear W19710894522015 @default.
• W1971089452 countsByYear W19710894522016 @default.
• W1971089452 countsByYear W19710894522019 @default.
• W1971089452 countsByYear W19710894522020 @default.
• W1971089452 countsByYear W19710894522021 @default.
• W1971089452 countsByYear W19710894522022 @default.
• W1971089452 crossrefType "journal-article" @default.
• W1971089452 hasAuthorship W1971089452A5048202574 @default.
• W1971089452 hasAuthorship W1971089452A5055295106 @default.
• W1971089452 hasAuthorship W1971089452A5062514178 @default.
• W1971089452 hasAuthorship W1971089452A5063007213 @default.
• W1971089452 hasAuthorship W1971089452A5085008271 @default.
• W1971089452 hasBestOaLocation W19710894521 @default.
• W1971089452 hasConcept C126322002 @default.
• W1971089452 hasConcept C141071460 @default.
• W1971089452 hasConcept C2776689292 @default.
• W1971089452 hasConcept C2778789114 @default.
• W1971089452 hasConcept C2778881276 @default.
• W1971089452 hasConcept C2780014101 @default.
• W1971089452 hasConcept C2780920261 @default.
• W1971089452 hasConcept C2780959883 @default.
• W1971089452 hasConcept C42219234 @default.
• W1971089452 hasConcept C66112548 @default.
• W1971089452 hasConcept C71924100 @default.
• W1971089452 hasConcept C89560881 @default.
• W1971089452 hasConceptScore W1971089452C126322002 @default.
• W1971089452 hasConceptScore W1971089452C141071460 @default.
• W1971089452 hasConceptScore W1971089452C2776689292 @default.
• W1971089452 hasConceptScore W1971089452C2778789114 @default.
• W1971089452 hasConceptScore W1971089452C2778881276 @default.
• W1971089452 hasConceptScore W1971089452C2780014101 @default.
• W1971089452 hasConceptScore W1971089452C2780920261 @default.
• W1971089452 hasConceptScore W1971089452C2780959883 @default.
• W1971089452 hasConceptScore W1971089452C42219234 @default.
• W1971089452 hasConceptScore W1971089452C66112548 @default.
• W1971089452 hasConceptScore W1971089452C71924100 @default.
• W1971089452 hasConceptScore W1971089452C89560881 @default.
• W1971089452 hasIssue "3" @default.
• W1971089452 hasLocation W19710894521 @default.
• W1971089452 hasLocation W19710894522 @default.
• W1971089452 hasLocation W19710894523 @default.
• W1971089452 hasOpenAccess W1971089452 @default.
• W1971089452 hasPrimaryLocation W19710894521 @default.
• W1971089452 hasRelatedWork W1504009397 @default.
• W1971089452 hasRelatedWork W1971373881 @default.
• W1971089452 hasRelatedWork W1973719738 @default.
• W1971089452 hasRelatedWork W1974519130 @default.
• W1971089452 hasRelatedWork W1999666547 @default.
• W1971089452 hasRelatedWork W2105488322 @default.
• W1971089452 hasRelatedWork W2332407793 @default.
• W1971089452 hasRelatedWork W2530803726 @default.
• W1971089452 hasRelatedWork W4200371415 @default.
• W1971089452 hasRelatedWork W43131185 @default.
• W1971089452 hasVolume "90" @default.
• W1971089452 isParatext "false" @default.
• W1971089452 isRetracted "false" @default.
• W1971089452 magId "1971089452" @default.

• next