Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971170015> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W1971170015 endingPage "219" @default.
- W1971170015 startingPage "207" @default.
- W1971170015 abstract "Celiac disease is a common and lifelong food intolerance, affecting approximately 1% of the population. Because of a mechanism not completely understood, the ingestion of wheat gluten, and of homologue proteins of barley and rye, induces in genetically predisposed individuals pronounced inflammatory reactions mainly at the site of small intestine. Gluten, the triggering factor, is a complex protein mixture highly resistant to the gastrointestinal enzymatic proteolysis, and this results in the presence of large, and potentially immunogenic, peptides at the intestinal mucosa surface. During the last decade, several studies have defined gluten peptides able to stimulate adaptive T cells, of either CD4 or CD8 phenotype, and to activate innate (non T) immune cells. This review examines the complete repertoire of gluten peptides recognized by celiac T cells and discusses the several translational implications that the identification of these epitopes opens. Keywords: Celiac disease, glutn epitopes, T cells assays" @default.
- W1971170015 created "2016-06-24" @default.
- W1971170015 creator A5030112845 @default.
- W1971170015 creator A5051142618 @default.
- W1971170015 creator A5056192204 @default.
- W1971170015 date "2012-05-01" @default.
- W1971170015 modified "2023-10-16" @default.
- W1971170015 title "Repertoire of Gluten Peptides Active in Celiac Disease Patients: Perspectives For Translational Therapeutic Applications" @default.
- W1971170015 doi "https://doi.org/10.2174/187153012800493549" @default.
- W1971170015 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22385112" @default.
- W1971170015 hasPublicationYear "2012" @default.
- W1971170015 type Work @default.
- W1971170015 sameAs 1971170015 @default.
- W1971170015 citedByCount "42" @default.
- W1971170015 countsByYear W19711700152012 @default.
- W1971170015 countsByYear W19711700152013 @default.
- W1971170015 countsByYear W19711700152014 @default.
- W1971170015 countsByYear W19711700152015 @default.
- W1971170015 countsByYear W19711700152016 @default.
- W1971170015 countsByYear W19711700152017 @default.
- W1971170015 countsByYear W19711700152018 @default.
- W1971170015 countsByYear W19711700152019 @default.
- W1971170015 countsByYear W19711700152020 @default.
- W1971170015 countsByYear W19711700152021 @default.
- W1971170015 countsByYear W19711700152023 @default.
- W1971170015 crossrefType "journal-article" @default.
- W1971170015 hasAuthorship W1971170015A5030112845 @default.
- W1971170015 hasAuthorship W1971170015A5051142618 @default.
- W1971170015 hasAuthorship W1971170015A5056192204 @default.
- W1971170015 hasConcept C126322002 @default.
- W1971170015 hasConcept C147483822 @default.
- W1971170015 hasConcept C195616568 @default.
- W1971170015 hasConcept C203014093 @default.
- W1971170015 hasConcept C2776336767 @default.
- W1971170015 hasConcept C2779134260 @default.
- W1971170015 hasConcept C2908647359 @default.
- W1971170015 hasConcept C55493867 @default.
- W1971170015 hasConcept C71924100 @default.
- W1971170015 hasConcept C86803240 @default.
- W1971170015 hasConcept C8891405 @default.
- W1971170015 hasConcept C99454951 @default.
- W1971170015 hasConceptScore W1971170015C126322002 @default.
- W1971170015 hasConceptScore W1971170015C147483822 @default.
- W1971170015 hasConceptScore W1971170015C195616568 @default.
- W1971170015 hasConceptScore W1971170015C203014093 @default.
- W1971170015 hasConceptScore W1971170015C2776336767 @default.
- W1971170015 hasConceptScore W1971170015C2779134260 @default.
- W1971170015 hasConceptScore W1971170015C2908647359 @default.
- W1971170015 hasConceptScore W1971170015C55493867 @default.
- W1971170015 hasConceptScore W1971170015C71924100 @default.
- W1971170015 hasConceptScore W1971170015C86803240 @default.
- W1971170015 hasConceptScore W1971170015C8891405 @default.
- W1971170015 hasConceptScore W1971170015C99454951 @default.
- W1971170015 hasIssue "2" @default.
- W1971170015 hasLocation W19711700151 @default.
- W1971170015 hasLocation W19711700152 @default.
- W1971170015 hasOpenAccess W1971170015 @default.
- W1971170015 hasPrimaryLocation W19711700151 @default.
- W1971170015 hasRelatedWork W2013925870 @default.
- W1971170015 hasRelatedWork W2022236080 @default.
- W1971170015 hasRelatedWork W2023869132 @default.
- W1971170015 hasRelatedWork W2124827015 @default.
- W1971170015 hasRelatedWork W2145223056 @default.
- W1971170015 hasRelatedWork W2414203182 @default.
- W1971170015 hasRelatedWork W2951303472 @default.
- W1971170015 hasRelatedWork W3112940496 @default.
- W1971170015 hasRelatedWork W3162344223 @default.
- W1971170015 hasRelatedWork W4318039497 @default.
- W1971170015 hasVolume "12" @default.
- W1971170015 isParatext "false" @default.
- W1971170015 isRetracted "false" @default.
- W1971170015 magId "1971170015" @default.
- W1971170015 workType "article" @default.