FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1971234083> ?p ?o ?g. }

• W1971234083 endingPage "249" @default.
• W1971234083 startingPage "241" @default.
• W1971234083 abstract "The release of [3H]GABA from slices of rat substantia nigra pars reticulata induced by increasing extracellular K+ from 6 to 15 mM in the presence of 10 microM sulpiride was inhibited by 73 +/- 3% by 1 microM SCH 23390, consistent with a large component of release dependent upon D1 receptor activation. The histamine H3 receptor-selective agonist immepip (1 microM) and the non-selective agonist histamine (100 microM) inhibited [3H]GABA release by 78 +/- 2 and 80 +/- 2%, respectively. The inhibition by both agonists was reversed by the H3 receptor antagonist thioperamide (1 microM). However, in the presence of 1 microM SCH 23390 depolarization-induced release of [3H]GABA was not significantly decreased by 1 microM immepip. In rats depleted of dopamine by pretreatment with reserpine, immepip no longer inhibited control release of [3H]GABA, but in the presence of 1 microM SKF 38393, which produced a 7 +/- 1-fold stimulation of release, immepip reduced the release to a level not statistically different from that in the presence of immepip alone. Immepip (1 microM) also inhibited the depolarization-induced release of [3H]dopamine from substantia nigra pars reticulata slices, by 38 +/- 3%. The evidence is consistent with the proposition that activation of histamine H3 receptors leads to the selective inhibition of the component of depolarization-induced [3H]GABA release in substantia nigra pars reticulata slices which is dependent upon D1 receptor activation. This appears to be largely an action at the terminals of the striatonigral GABA projection neurons, which may be enhanced by a partial inhibition of dendritic [3H]dopamine release." @default.
• W1971234083 created "2016-06-24" @default.
• W1971234083 creator A5004141146 @default.
• W1971234083 creator A5015645943 @default.
• W1971234083 creator A5025355312 @default.
• W1971234083 creator A5033997788 @default.
• W1971234083 creator A5080603956 @default.
• W1971234083 date "1997-06-01" @default.
• W1971234083 modified "2023-10-18" @default.
• W1971234083 title "Histamine H3 receptor activation selectively inhibits dopamine D1 receptor-dependent [3H]GABA release from depolarization-stimulated slices of rat substantia nigra pars reticulata" @default.
• W1971234083 cites W1963510189 @default.
• W1971234083 cites W1966267057 @default.
• W1971234083 cites W1975870401 @default.
• W1971234083 cites W1979692030 @default.
• W1971234083 cites W1982358202 @default.
• W1971234083 cites W1990368217 @default.
• W1971234083 cites W1991464169 @default.
• W1971234083 cites W1993778555 @default.
• W1971234083 cites W1996956700 @default.
• W1971234083 cites W2006660473 @default.
• W1971234083 cites W2007264185 @default.
• W1971234083 cites W2013469891 @default.
• W1971234083 cites W2021876207 @default.
• W1971234083 cites W2028073821 @default.
• W1971234083 cites W2034697832 @default.
• W1971234083 cites W2035645280 @default.
• W1971234083 cites W2039031830 @default.
• W1971234083 cites W2046302119 @default.
• W1971234083 cites W2050912538 @default.
• W1971234083 cites W2052175351 @default.
• W1971234083 cites W2052543207 @default.
• W1971234083 cites W2070561051 @default.
• W1971234083 cites W2075212681 @default.
• W1971234083 cites W2077008759 @default.
• W1971234083 cites W2077687762 @default.
• W1971234083 cites W2078305868 @default.
• W1971234083 cites W2078623903 @default.
• W1971234083 cites W2079416717 @default.
• W1971234083 cites W2083618039 @default.
• W1971234083 cites W2091902125 @default.
• W1971234083 cites W2108497122 @default.
• W1971234083 cites W2118002215 @default.
• W1971234083 cites W2127695246 @default.
• W1971234083 cites W2136631073 @default.
• W1971234083 cites W2156174515 @default.
• W1971234083 doi "https://doi.org/10.1016/s0306-4522(97)00100-0" @default.
• W1971234083 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9252235" @default.
• W1971234083 hasPublicationYear "1997" @default.
• W1971234083 type Work @default.
• W1971234083 sameAs 1971234083 @default.
• W1971234083 citedByCount "128" @default.
• W1971234083 countsByYear W19712340832012 @default.
• W1971234083 countsByYear W19712340832013 @default.
• W1971234083 countsByYear W19712340832014 @default.
• W1971234083 countsByYear W19712340832015 @default.
• W1971234083 countsByYear W19712340832016 @default.
• W1971234083 countsByYear W19712340832017 @default.
• W1971234083 countsByYear W19712340832018 @default.
• W1971234083 countsByYear W19712340832019 @default.
• W1971234083 countsByYear W19712340832020 @default.
• W1971234083 countsByYear W19712340832021 @default.
• W1971234083 countsByYear W19712340832022 @default.
• W1971234083 countsByYear W19712340832023 @default.
• W1971234083 crossrefType "journal-article" @default.
• W1971234083 hasAuthorship W1971234083A5004141146 @default.
• W1971234083 hasAuthorship W1971234083A5015645943 @default.
• W1971234083 hasAuthorship W1971234083A5025355312 @default.
• W1971234083 hasAuthorship W1971234083A5033997788 @default.
• W1971234083 hasAuthorship W1971234083A5080603956 @default.
• W1971234083 hasConcept C120069818 @default.
• W1971234083 hasConcept C126322002 @default.
• W1971234083 hasConcept C134018914 @default.
• W1971234083 hasConcept C137183658 @default.
• W1971234083 hasConcept C170493617 @default.
• W1971234083 hasConcept C185592680 @default.
• W1971234083 hasConcept C2778938600 @default.
• W1971234083 hasConcept C2778997900 @default.
• W1971234083 hasConcept C2779917531 @default.
• W1971234083 hasConcept C2780938664 @default.
• W1971234083 hasConcept C4141045 @default.
• W1971234083 hasConcept C513476851 @default.
• W1971234083 hasConcept C55493867 @default.
• W1971234083 hasConcept C63180777 @default.
• W1971234083 hasConcept C71924100 @default.
• W1971234083 hasConcept C86803240 @default.
• W1971234083 hasConcept C98274493 @default.
• W1971234083 hasConceptScore W1971234083C120069818 @default.
• W1971234083 hasConceptScore W1971234083C126322002 @default.
• W1971234083 hasConceptScore W1971234083C134018914 @default.
• W1971234083 hasConceptScore W1971234083C137183658 @default.
• W1971234083 hasConceptScore W1971234083C170493617 @default.
• W1971234083 hasConceptScore W1971234083C185592680 @default.
• W1971234083 hasConceptScore W1971234083C2778938600 @default.
• W1971234083 hasConceptScore W1971234083C2778997900 @default.
• W1971234083 hasConceptScore W1971234083C2779917531 @default.
• W1971234083 hasConceptScore W1971234083C2780938664 @default.
• W1971234083 hasConceptScore W1971234083C4141045 @default.
• W1971234083 hasConceptScore W1971234083C513476851 @default.

• next