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- W1971236398 abstract "Fifty-six patients with acute, nonlymphatic leukemia in the initial phase were studied. The poor prognostic signs were excessive in vitro growth, many HLA-DR-positive cells, or a low ratio of leukemic cell antigenicity to HLA-DR positivity and age. The cells from older patients formed more clusters (P < 0.05), and they had less capacity to stimulate normal allogeneic lymphocytes (P < 0.05) than those from younger patients. Cells forming many clusters also were more often (P < 0.01) HLA-DR-positive than those forming few clusters. It is suggested that the prognosis in old patients with acute leukemia is poor in part because their leukemic cells have characteristics different from those of young patients." @default.
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- W1971236398 date "1984-02-01" @default.
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- W1971236398 title "Difference between young and old patients in characteristics of leukemic cells: Older patients have cells growing excessively in vitro, with low antigenicity despite high HLA-DR antigens" @default.
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- W1971236398 doi "https://doi.org/10.1002/ajh.2830160203" @default.
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